5 completed, 1 terminated, 1 withdrawn. 7 Phase 1.
By phase and status
Follow Non-squamous Non-small Cell Lung Cancer: new trials by email Literature Review of Non-squamous Non-small Cell Lung Cancer trials Research Report on Non-squamous Non-small Cell Lung Cancer
Trials (filtered) newest first · largest first
All 7 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
A Phase 1 Safety, Tolerability, and Pharmacokinetics Study of AMG 794 With Claudin 6-positive Non-small Cell Lung Cancer, Epithelial Ovarian Cancer, and Other Malignant Solid Tumor Indications
AMG 794 - Non-squamous Non-small Cell Lung Cancer, Epithelial Ovarian Cancer | Phase 1 | Terminated | 3 | 2023-02-28 | 2025-10-08 |
Study of Nintedanib Plus Bevacizumab in Advanced Solid Tumors
Nintedanib, Bevacizumab - Renal Cell Carcinoma, Colorectal Adenocarcinoma | Phase 1 | Completed | 21 | 2016-06-09 | 2018-07-10 |
A Study of RO5083945 in Combination With Cisplatin and Gemcitabine or Carboplatin and Paclitaxel in Patients With Advanced or Recurrent Non-Small Cell Lung Cancer of Squamous Histology Who Have Not Received Prior Chemotherapy for The Metastatic Disease
RO5083945, carboplatin, cisplatin - Non-Squamous Non-Small Cell Lung Cancer | Phase 1 | Withdrawn | | 2014-07-01 | 2016-11-04 |
A Study to Evaluate the Safety and Pharmacology of DNIB0600A in Participants With Platinum-Sensitive Ovarian Cancer or Non-Squamous Non-small Cell Lung Cancer
Bevacizumab, Carboplatin, DNIB0600A - Non-Squamous Non-Small Cell Lung Cancer | Phase 1 | Completed | 41 | 2013-12-16 | 2017-10-04 |
A Study of the Safety and Pharmacology Of PI3-Kinase Inhibitor GDC-0941 In Combination With Either Paclitaxel And Carboplatin (With or Without Bevacizumab) or Pemetrexed, Cisplatin, And Bevacizumab in Patients With Advanced Non-Small Cell Lung Cancer
GDC-0941, bevacizumab, carboplatin - Non-Squamous Non-Small Cell Lung Cancer | Phase 1 | Completed | 65 | 2009-10-01 | 2016-11-02 |
A Study of Avastin (Bevacizumab) in Combination With Thoracic Radiation and Chemotherapy in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer.
bevacizumab [Avastin], cisplatin, etoposide - Non-Squamous Non-Small Cell Lung Cancer | Phase 1 | Completed | 1 | 2009-04-01 | 2016-11-02 |
A Feasibility Trial of Avastin (Bevacizumab) in Combination With Concomitant Chemoradiation (Cisplatin and Vinorelbine) in Patients With Locally Advanced Non-Squamous Non-Small Cell Lung Cancer.
bevacizumab [Avastin], cisplatin, vinorelbine - Non-Squamous Non-Small Cell Lung Cancer | Phase 1 | Completed | 6 | 2008-12-01 | 2016-11-02 |
Narrower conditions
Carcinoma, Ovarian Epithelial (1) · Carcinoma, Renal Cell (1) · Uterine Cervical Neoplasms (1)
Broader conditions
Carcinoma (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Genital Diseases (2) · Genital Diseases, Female (2) · Genital Neoplasms, Female (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Neoplasms by Site (2) · Neoplasms, Glandular and Epithelial (2) · Urogenital Diseases (2) · Urogenital Neoplasms (2) · Adenocarcinoma (1) · Adnexal Diseases (1) · Endocrine Gland Neoplasms (1)
Interventions
Bevacizumab (5) · Cisplatin (4) · Carboplatin (3) · Paclitaxel (2) · 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine (1) · Etoposide (1) · Gemcitabine (1) · Pemetrexed (1) · Vinorelbine (1) · imgatuzumab (1) · lifastuzumab vedotin (1) · nintedanib (1)
Sponsors
Hoffmann-La Roche (3) · Genentech, Inc. (2) · Amgen (1) · University of Alabama at Birmingham (1)
Countries
United States (4) · Netherlands (2) · Australia (1) · Canada (1) · France (1) · Switzerland (1) · United Kingdom (1)
Top investigators
Francisco Robert, MD (1)
Results publications
PMID 30603797
NIH funding
2008 (1)