Myelofibrosis (MF): Clinical Trials

3 trials for Myelofibrosis (MF), newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

1 active not recruiting, 1 completed, 1 not yet recruiting. 3 Phase 3, 1 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 33Active not recruiting 1, Completed 1, Not yet recruiting 1
Phase 21Not yet recruiting 1

Follow Myelofibrosis (MF): new trials by email Literature Review of Myelofibrosis (MF) trials Research Report on Myelofibrosis (MF)

Trials (filtered) newest first · largest first

All 3 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Luspatercept in Preventing Poor Erythroid Engraftment for Hematological Malignancies With Moderate to Severe Myelofibrosis
Luspatercept, Control - Luspatercept, Poor Erythroid Engraftment
Phase 2 / Phase 3Not yet recruitingNanfang Hospital, Southern Medical University1962026-05-012026-04-20
Study of Oral Navitoclax Tablet In Combination With Oral Ruxolitinib Tablet When Compared With Oral Ruxolitinib Tablet To Assess Change In Spleen Volume In Adult Participants With Myelofibrosis
Placebo for Navitoclax, Ruxolitinib, Navitoclax - Myelofibrosis (MF)
Phase 3CompletedAbbVie2522020-09-292026-03-23
Study of Oral Navitoclax Tablet in Combination With Oral Ruxolitinib Tablet Versus Best Available Therapy to Assess Change in Spleen Volume in Adult Participants With Relapsed/Refractory Myelofibrosis
Navitoclax, Ruxolitinib, Best Available Therapy (BAT) - Myelofibrosis (MF)
Phase 3Active not recruitingAbbVie3302020-08-312026-01-09

Narrower conditions

Primary Myelofibrosis (3)  ·  Neoplasms (2)  ·  Hematologic Neoplasms (1)

Broader conditions

Bone Marrow Diseases (3)  ·  Hematologic Diseases (3)  ·  Hemic and Lymphatic Diseases (3)  ·  Myeloproliferative Disorders (3)  ·  Neoplasms (1)  ·  Neoplasms by Site (1)

Interventions

navitoclax (2)  ·  ruxolitinib (2)  ·  luspatercept (1)

Sponsors

AbbVie (2)  ·  Nanfang Hospital, Southern Medical University (1)

Countries

Australia (2)  ·  Austria (2)  ·  Belgium (2)  ·  Bulgaria (2)  ·  Canada (2)  ·  Croatia (2)  ·  France (2)  ·  Germany (2)  ·  Greece (2)  ·  Israel (2)  ·  Italy (2)  ·  Japan (2)  ·  New Zealand (2)  ·  Russia (2)  ·  Serbia (2)

Top investigators

Qifa Liu (1)

Results publications

PMID 20424252, PMID 28096091, PMID 29895954, PMID 34002031, PMID 37311468, PMID 42842696

NIH funding

2023 (1)