3 completed, 1 terminated. 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Completed 3, Terminated 1 |
Follow Mucopolysaccharidosis I: new trials by email Literature Review of Mucopolysaccharidosis I trials Research Report on Mucopolysaccharidosis I
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| China Post-marketing Surveillance (PMS) Study of Aldurazyme® Laronidase - Mucopolysaccharidosis I | Phase 4 | Completed | Genzyme, a Sanofi Company | 12 | 2021-10-28 | 2025-09-17 |
| A Study of the Effect of Aldurazyme® (Laronidase) Treatment on Lactation in Female Patients With Mucopolysaccharidosis I (MPS I) and Their Breastfed Infants Laronidase - Mucopolysaccharidosis I, Hurler's Syndrome | Phase 4 | Terminated | Genzyme, a Sanofi Company | 2 | 2010-10-22 | 2024-02-20 |
| A Dose-optimization Study of Aldurazyme® (Laronidase) in Patients With Mucopolysaccharidosis I (MPS I) Disease Aldurazyme (Recombinant Human Alpha-L-Iduronidase) - Mucopolysaccharidosis I, Hurler's Syndrome | Phase 4 | Completed | Genzyme, a Sanofi Company | 34 | 2004-12-01 | 2015-04-03 |
| A Study Investigating the Relationship Between the Development of Laronidase Antibody and Urinary GAG (Glycosaminoglycan) Levels in Aldurazyme® Treated Patients laronidase - Mucopolysaccharidosis I, Hurler's Syndrome | Phase 4 | Completed | Genzyme, a Sanofi Company | 25 | 2004-07-01 | 2014-05-05 |
Carbohydrate Metabolism, Inborn Errors (4) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (4) · Connective Tissue Diseases (4) · Genetic Diseases, Inborn (4) · Lysosomal Storage Diseases (4) · Metabolic Diseases (4) · Metabolism, Inborn Errors (4) · Mucinoses (4) · Mucopolysaccharidoses (4) · Nutritional and Metabolic Diseases (4) · Skin and Connective Tissue Diseases (4)
Iduronidase (4)
Brazil (1) · Canada (1) · China (1) · Italy (1) · United States (1)