3 not yet recruiting, 1 recruiting. 3 Phase 1, 1 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Not yet recruiting 2, Recruiting 1 |
| Not applicable | 1 | Not yet recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
Follow High-Grade Glioma (HGG): new trials by email Literature Review of High-Grade Glioma (HGG) trials Research Report on High-Grade Glioma (HGG)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Feasibility Assessment of a Medical Device for Tumour Cell Retention and Radiotherapy Sensitization in Patients With Suspected High-grade Glioma GlioHook device - Glioma, High-Grade Glioma (HGG) | Not applicable | Not yet recruiting | Batea Oncology | 15 | 2026-10-30 | 2026-07-27 |
| Tarlatamab Treatment Before and After Surgery in Surgically Resectable Recurrent High-grade Glioma: a Window of Opportunity Study (TARLAGLIA Study) Tarlatamab - High-Grade Glioma (HGG) | Phase 1 | Not yet recruiting | Vall d'Hebron Institute of Oncology | 10 | 2026-10-01 | 2026-08-26 |
| A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressive High-Grade Glioma or Posterior Fossa-A Ependymoma Cemiplimab, Cemiplimab+Fianlimab Fixed Dose Combination (FDC) - High-Grade Glioma (HGG), Posterior Fossa-A Ependymoma | Phase 1 / Phase 2 | Not yet recruiting | Regeneron Pharmaceuticals | 120 | 2026-08-31 | 2026-05-05 |
| Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021) Everolimus, Trametinib - Recurrent World Health Organization (WHO) Grade II Glioma, Low-grade Glioma | Phase 1 | Recruiting | University of California, San Francisco | 50 | 2020-12-09 | 2026-08-18 |
Glioma (4) · Ependymoma (1) · Neoplasms (1) · Recurrence (1)
Neoplasms by Histologic Type (4) · Neoplasms, Germ Cell and Embryonal (4) · Neoplasms, Glandular and Epithelial (4) · Neoplasms, Nerve Tissue (4) · Neoplasms, Neuroepithelial (4) · Neuroectodermal Tumors (4) · Neoplasms (3) · Disease Attributes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Everolimus (1) · cemiplimab (1) · trametinib (1)
Batea Oncology (1) · Regeneron Pharmaceuticals (1) · University of California, San Francisco (1) · Vall d'Hebron Institute of Oncology (1)
Spain (2) · United States (1)
Sabine Mueller (1)
2025 (2)