10 unknown. 10 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Unknown 10 |
| Phase 2 | 2 | Unknown 2 |
Follow B-Cell Lymphoma: new trials by email Literature Review of B-Cell Lymphoma trials Research Report on B-Cell Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Novel Anti-CD19 CAR-T in Patients With r/r B-Cell Malignancies Anti-CD19 Autologous CAR-T Cell Infusion - B-Cell Leukemia, B-Cell Lymphoma | Phase 1 / Phase 2 | Unknown | 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China | 60 | 2023-07-01 | 2023-07-11 |
| Allogeneic NK T-Cells Expressing CD19 Specific CAR in B-Cell Malignancies KUR-502 - NHL, Relapsed, Adult, B-cell Lymphoma | Phase 1 | Unknown | Athenex, Inc. | 36 | 2022-10-01 | 2023-05-18 |
| Natural Killer (NK) Cell Therapy for B-Cell Malignancies QN-019a, Rituximab, Cyclophosphamid - B-cell Lymphoma, B-cell Acute Lymphoblastic Leukemia | Phase 1 | Unknown | Zhejiang University | 24 | 2021-11-04 | 2022-05-18 |
| Clinical Study of CAR-iNKT Cells in the Treatment of Relapsed/Refractory/High-risk B-cell Tumors hCD19.IL15.CAR-iNKT - Acute Lymphoblastic Leukemia, B-cell Lymphoma | Phase 1 | Unknown | Kai Lin Xu; Jun Nian Zheng | 20 | 2021-03-19 | 2021-03-29 |
| Universal Chimeric Antigen Receptor-modified AT19 Cells for CD19+ Relapsed/Refractory Hematological Malignancies Fludarabine + Cyclophosphamide + CAR-NK-CD19 Cells - Acute Lymphoblastic Leukemia, Chronic Lymphoblastic Leukemia | Phase 1 | Unknown | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 27 | 2021-03-10 | 2021-03-15 |
| CD19-targeting CAR T Cells in Relapsed or Refractory CD19 Positive B-cell Malignancies CD19 CAR T - B-cell Malignancy, B-cell Lymphoma | Phase 1 | Unknown | Shanghai Tong Ren Hospital | 9 | 2018-04-24 | 2020-11-05 |
| Efficacy and Safety of PZ01 Treatment in Patients With r/r CD19+ B-cell Acute Lymphoblastic Leukemia/B Cell Lymphoma PZ01 CAR-T cells - B-cell Acute Lymphoblastic Leukemia, B-cell Lymphoma | Phase 1 | Unknown | Pinze Lifetechnology Co. Ltd. | 50 | 2017-10-01 | 2017-09-15 |
| A Phase I Study of AC0010 in Patients With CLL/ SLL, MCL, DLBCL and Other NHL AC0010MA - B-cell Lymphoma | Phase 1 | Unknown | Hangzhou ACEA Pharmaceutical Research Co., Ltd. | 184 | 2017-03-17 | 2019-02-01 |
| CAR T Cells for Refractory B Cell Malignancy Autologous CD19-targeting CAR T cells - B-Cell Leukemia, B-Cell Lymphoma | Phase 1 / Phase 2 | Unknown | Hebei Senlang Biotechnology Inc., Ltd. | 10 | 2016-06-01 | 2017-04-28 |
| Autologous CD19 CAR T Cells in Relapsed or Refractory B-cell Lymphoma autologous anti-CD19 CAR T cells - B-cell Lymphoma | Phase 1 | Unknown | Peking University | 25 | 2016-06-01 | 2019-02-25 |
Lymphoma, B-Cell (10) · Burkitt Lymphoma (3) · Leukemia, B-Cell (3) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (3) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Dendritic Cell Sarcoma, Interdigitating (1) · Leukemia (1) · Lymphoma (1) · Lymphoma, Non-Hodgkin (1) · Recurrence (1)
Hemic and Lymphatic Diseases (10) · Immune System Diseases (10) · Immunoproliferative Disorders (10) · Lymphatic Diseases (10) · Lymphoproliferative Disorders (10) · Neoplasms (10) · Neoplasms by Histologic Type (10) · Lymphoma (9) · Lymphoma, Non-Hodgkin (9) · Hematologic Diseases (5) · Leukemia, Lymphoid (5) · Leukemia (4) · DNA Virus Infections (3) · Disease Attributes (3) · Epstein-Barr Virus Infections (3)
Cyclophosphamide (2) · fludarabine (2) · Etoposide (1) · Rituximab (1) · abivertinib (1)
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China (1) · Athenex, Inc. (1) · Hangzhou ACEA Pharmaceutical Research Co., Ltd. (1) · Hebei Senlang Biotechnology Inc., Ltd. (1) · Kai Lin Xu; Jun Nian Zheng (1) · Peking University (1) · Pinze Lifetechnology Co. Ltd. (1) · Shanghai Tong Ren Hospital (1) · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (1) · Zhejiang University (1)
China (9) · United States (1)
Carlos Ramos, MD (1) · He Huang, PhD (1) · Heng Mei, M.D., Ph.D (1) · Jianmin Luo, PhD & MD (1) · Jie Jin, MD (1) · Jun Zhu, MD (1) · Junnian Zheng, Ph.D (1) · Kailin Xu, Ph.d (1) · Ligen Liu (1) · Sanbin Wang, Professor (1) · Shengdian Wang (1)