Comparison of Treatment Modalities in Myofascial Pain Syndrome

NCT07413770 — Not applicable, Completed, 60 participants, Biruni University

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Effects of Classical Massage in Individuals With Myofascial Pain Syndrome: A Randomized Controlled Trial

RegistryNCT07413770
StatusCompleted
PhaseNot applicable
Study typeInterventional; randomized, parallel, masking: double, treatment
Enrollment60 (Actual)
SponsorBiruni University (Other)
ConditionsMyofascial Pain Dysfunction Syndrome, Pain, Massage Therapy, Physiotherapy
InterventionsConventional treatment, Therapeutic Massage, combined treatment (Other)
Datesstart 2025-12-29, primary completion 2026-02-20, completion 2026-02-20, first posted 2026-02-17, last updated 2026-05-19
Locations1 site in Turkey (Türkiye)

Related Papers Related Patents Related Grants Related Experts
All trials for Myofascial Pain Dysfunction Syndrome All trials for Pain All trials of Conventional treatment All trials of Therapeutic Massage

-Summary

The aim of this study is to evaluate the effects of classical massage on pain, muscle sensitivity, muscle activity, functional status, and quality of life in individuals with myofascial pain syndrome, and to compare the effectiveness of classical massage applied alone versus in combination with a conventional physiotherapy program.

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+Arms and interventions

ArmTypeInterventionsDescription
Conventional PhysiotherapyExperimentalOther: Conventional treatment
Therapeutic massageExperimentalOther: Therapeutic Massage
Combined treatmentExperimentalOther: combined treatment
  • Conventional treatment (Other): Participants inthis group will receive a conventional physiotherapy program consisting of moist heat application for 15 minutes, pain-limited static stretching of the upper trapezius muscle (30-second stretch with 10-second rest, repeated five times), electrotherapy modalities (TENS, ultrasound, and infrared therapy), and postural education with a home exercise program for approximately 10 minutes.
  • Therapeutic Massage (Other): Participants in this group will receive a 20-minute therapeutic massage intervention identical in technique and sequence to the massage component applied in combined group, targeting the neck and upper back muscles using Swedish massage techniques, without additional conventional physiotherapy modalities.
  • combined treatment (Other): Participants in this group will receive a combined intervention consisting of a conventional physiotherapy program together with a 20-minute therapeutic massage applied to the neck and upper back muscles (erector spinae, upper and middle trapezius, and levator scapulae), delivered according to Swedish massage principles, including effleurage, kneading, and deep friction techniques targeting active trigger points.

+Outcome measures

Primary outcomes

  • Pain Intensity [6 weeks]: The primary outcome of this study is pain intensity, will be assessed using the Visual Analog Scale (VAS), a 10-cm scale ranging from 0 (no pain) to 10 (worst imaginable pain), with higher scores indicating greater pain intensity.

Secondary outcomes

  • Pressure Pain Threshold-Algometer [6 weeks]: Muscle sensitivity will be evaluated using a pressure algometer applied over the upper trapezius trigger point, where higher values indicate reduced tenderness. Results will be recorded in kg/cm².
  • Muscle Activity [6 weeks]: Muscle activity will be evaluated using surface electromyography (EMG) through root mean square (RMS) values recorded at rest and during 90 degrees of shoulder abduction. Higher RMS values indicate greater muscle activation. Results will ve recorded in µV.
  • Functional Status (Neck Disability Index) [6 weeks]: Functional disability related to neck pain will be evaluated using the Neck Disability Index (NDI). Total score ranges from 0 to 50; higher scores indicate greater disability. Lower scores reflect improved functional status.
  • Quality of Life (SF-12) [6 weeks]: Health-related quality of life will be assessed using the Short Form-12 questionnaire. Physical Component Summary (PCS) and Mental Component Summary (MCS) scores. Higher scores indicate better quality of life.

+Eligibility

Sex: All, ages: 30 Years to 50 Years

Inclusion Criteria:

* Diagnosis of myofascial pain syndrome confirmed by a physical medicine and rehabilitation physician, according to the criteria of Travell and Simons (1992)
* Male or female participants aged 30-50 years
* Presence of at least one active trigger point in the upper trapezius muscle confirmed by palpation
* Pain radiating to the neck and upper extremity persisting for at least 3 months
* Pain intensity of ≥4/10 on the Visual Analog Scale (VAS)
* Functional impairment indicated by a Neck Disability Index (NDI) score ≥10/50 (≥20%)
* Written informed consent

Exclusion Criteria:

* Presence of diagnosed systemic musculoskeletal or rheumatologic disorders (e.g., fibromyalgia, rheumatoid arthritis)
* Signs or symptoms of neuropathic pain or cervical radiculopathy
* Conditions contraindicating massage therapy (e.g., skin infection, open wounds, bleeding disorders, active inflammation)
* Receipt of manual therapy, massage, dry needling, injections, or similar treatments targeting the affected region within the preceding 1 month
* Pregnancy or breastfeeding
* History of acute trauma, fracture, or surgical intervention involving the neck or shoulder region

+Locations (1)

FacilityCityCountryStatus
Biruni UniversityIstanbulTurkey (Türkiye)