Factors Associated With Breast Cancer Risks and Outcomes

NCT07294703 — Recruiting, 750 participants, Memorial Sloan Kettering Cancer Center

ClinicalTrials Daily · Areas · Conditions · Drugs · Sponsors ·

Genomic and Non-Genomic Factors Associated With Breast Cancer Risk Factors and Outcomes

Registry	NCT07294703
Status	Recruiting
Study type	Observational
Enrollment	750 (Estimated)
Sponsor	Memorial Sloan Kettering Cancer Center (Other)
Conditions	Breast Cancer
Interventions	Survey (Other)
Dates	start 2025-12-08, primary completion 2031-12-08 (estimated), completion 2031-12-08 (estimated), first posted 2025-12-19, last updated 2026-10-22
Locations	7 sites in United States

-Summary

The purpose of this study is to learn more about risks and outcomes of breast cancer in people with different backgrounds. Tissue and blood will be collected from participants for research purposes. Participants will complete questionnaires during their standard medical care. The study will not provide treatment for cancer or any other condition.

Expand all sections · Collapse all

+Arms and interventions

Arm	Type	Interventions	Description
Participants with a suspicious breast finding or new breast cancer diagnosis		Other: Survey	Participants with a suspicious breast finding who present to breast radiology at MSK for biopsy or a participants with a new breast cancer diagnosis who is a surgical candidate seen at MSK.

Survey (Other): Complete surveys: * Baseline (within 6 months of enrollment) * 1st follow-up survey (approx. 6 months to 12 months) * 2nd follow-up survey and/or blood collection (approx. 3 years +/- 6 months) * 3rd follow-up survey and/or blood collection (approx. 5 years +/- 6 months)

+Outcome measures

Primary outcomes

Recurrence Free Survival/RFS [5 years]: RFS as defined by the STEEP 2.0 guidelines

+Eligibility

Sex: Female, ages: 18 Years to any

Women 18 years and older who are patients with a suspicious breast finding who present to breast radiology at MSK for biopsy or any new breast cancer patient seen at MSK undergoing surgery.

Inclusion Criteria:

A patient cannot be considered eligible for this study unless the following conditions are met.

* Patients with a suspicious breast finding who present to breast radiology at MSK for biopsy or any new breast cancer patient who is a surgical candidate seen at MSK.
* Women 18 years of age and older are eligible to participate in the study.

Exclusion Criteria:

* Patients presenting with a suspicious breast mass or breast cancer less than 1 cm.
* Patients presenting to clinic with only microinvasion
* Patients who are less than 18 years of age
* Patients unable to complete the survey, including IDMC patients.

+Locations (7)

Facility	City	Country	Status
Memorial Sloan Kettering Cancer Center Basking Ridge (Limited Protocol Activities)	Basking Ridge, New Jersey	United States	Recruiting
Memorial Sloan Kettering Monmouth (All Protocol Activities)	Middletown, New Jersey	United States	Recruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)	Montvale, New Jersey	United States	Recruiting
Memorial Sloan Kettering Suffolk-Commack (Limited Protocol Activities)	Commack, New York	United States	Recruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)	Harrison, New York	United States	Recruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activites)	New York, New York	United States	Recruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activites)	Rockville Centre, New York	United States	Recruiting

+Investigators

Neha Goel, MD, MPH, Principal investigator, Memorial Sloan Kettering Cancer Center