Contralateral Adrenal Volume Predicts Duration of Postoperative Steroid Replacement Therapy in Non-ACTH-dependent Hypercortisolism

NCT07282223 — Completed, 121 participants, Peking University First Hospital

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Registry	NCT07282223
Status	Completed
Study type	Observational
Enrollment	121 (Actual)
Sponsor	Peking University First Hospital (Other)
Conditions	Cushing's Syndrome, Postoperative, Glucocorticoid, Prediction
Interventions	observational diagnostic model development (Other)
Dates	start 2017-08-01, primary completion 2025-04-01, completion 2025-04-01, first posted 2025-12-15, last updated 2025-12-15
Locations	1 site in China

-Summary

To identify preoperative factors influencing the duration of steroid replacement therapy after adrenalectomy/adrenal-sparing surgery in patients with non-ACTH-dependent hypercortisolism.

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+Arms and interventions

observational diagnostic model development (Other): observational diagnostic model development

+Outcome measures

Primary outcomes

Tumor volume [from 2017 to 2025]

+Eligibility

Sex: All, ages: 18 Years to 85 Years

Inclusion Criteria:

* In all, 111 patients (meadian age: 54years; 64.9% female) were included and received postoperative steroid replacement therapy, among whom 65 were diagnosed with subclinical Cushing's syndrome (SCS) and 46 with overt Cushing's syndrome (CS).

Exclusion Criteria:

* none

+Locations (1)

Facility	City	Country	Status
Department of Urology, Peking University First Hospital, Beijing, 100034	Beijing	China