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Polypropylene vs Polyglactin in Suturing of the Lung

NCT06115447 — Not yet recruiting, 100 participants, Assiut University

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RegistryNCT06115447
StatusNot yet recruiting
Study typeObservational
Enrollment100 (Estimated)
SponsorAssiut University (Other)
ConditionsLung Injury, Bleb Lung, Lung Cancer
Interventionslung suturing with polyglactin, ung suturing with polypropylene (Procedure)
Datesstart 2024-04-15 (estimated), primary completion 2026-04-30 (estimated), completion 2028-10-30 (estimated), first posted 2023-11-03, last updated 2023-11-03

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-Summary

Comparative study comparing polypropylene and Polyglactin in suturing of the lung

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+Detailed description

Lung tear or, pulmonary laceration is an injury in lung parenchyma, said injury can be caused by several reasons:

Blunt chest trauma Penetrating trauma such as stab wounds or firearm wounds Iatrogenic, such as faulty intercostal tube insertion

+Arms and interventions

ArmTypeInterventionsDescription
Polyglactin groupProcedure: lung suturing with polyglactinlung suturing with polyglactin
Polypropylene ArmProcedure: ung suturing with polypropylenelung suturing with Polypropylene
  • lung suturing with polyglactin (Procedure): lung suturing with polyglactin
  • ung suturing with polypropylene (Procedure): ung suturing with polypropylene

+Outcome measures

Primary outcomes

  • duration in days of intercostal tube air leak with each group [2 weeks]: Polypropylene vs Polyglactin

+Eligibility

Sex: All, ages: 18 Years to 65 Years

Inclusion Criteria:

* Patients admitted to Assiut University Hospital And will undergo surgery for lung tear repair.
* Patients admitted to Assiut University Hospital And will undergo surgery for bullectomy or lobectomy.

Exclusion Criteria:

* Patients with lung injury repaired with a stapler

+Publications

  • Regan T, Lawrence N. Comparison of poliglecaprone-25 and polyglactin-910 in cutaneous surgery. Dermatol Surg. 2013 Sep;39(9):1340-4. doi: 10.1111/dsu.12265. Epub 2013 Aug 13. PMID 23941601
  • Rendeki S, Molnar TF. Pulmonary contusion. J Thorac Dis. 2019 Feb;11(Suppl 2):S141-S151. doi: 10.21037/jtd.2018.11.53. PMID 30906578
  • Romby P, Carbon P, Westhof E, Ehresmann C, Ebel JP, Ehresmann B, Giege R. Importance of conserved residues for the conformation of the T-loop in tRNAs. J Biomol Struct Dyn. 1987 Dec;5(3):669-87. doi: 10.1080/07391102.1987.10506419. PMID 3078237

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