Incidence and Clinical Characteristics of Pulmonary Hypertension Secondary to ARDS in the Highland

NCT05166759 — Unknown, 100 participants, Southeast University, China

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Incidence and Clinical Characteristics of Pulmonary Hypertension Secondary to ARDS

Registry	NCT05166759
Status	Unknown
Study type	Observational
Enrollment	100 (Estimated)
Sponsor	Southeast University, China (Other); collaborators: Qinghai University
Conditions	ARDS
Interventions	Doppler ultrasound (Device)
Dates	start 2021-11-25, primary completion 2022-03-01 (estimated), completion 2022-12-01 (estimated), first posted 2021-12-22, last updated 2021-12-22
Locations	1 site in China

-Summary

The study is conducted in the affiliated hospital of Qinghai University .Patients in the department of Critical Care Medicine and Emergency Intensive Care Unit will be eligible for inclusion if they meet the Berlin criteria.Two researchers assess pulmonary artery pressure and right heart function of patients who are enrolled.

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+Arms and interventions

Doppler ultrasound (Device): Pulmonary artery pressure and right heart function will be assessed using Doppler ultrasound

+Outcome measures

Primary outcomes

Incidence of Pulmonary Hypertension Secondary to ARDS in the Highland [20/11/2021-20/12/2022]
ICU mortality ICU mortality [20/11/2021-20/12/2022]: Mortality during treatment in ICU
28-days mortality rate [20/11/2021-20/12/2022]: Mortality at 28 days of hospitalization

Secondary outcomes

Ventilator time [20/11/2021-20/12/2022]: Ventilator time in ICU
Hospital length of stay [20/11/2021-20/12/2022]: Total length of stay in hospital

Other outcomes

Right cardiac functionof Pulmonary Hypertension Secondary to ARDS in the Highland [20/11/2021-20/12/2022]

+Eligibility

Sex: All, ages: 18 Years to 80 Years

Inclusion Criteria:

Inclusion Criteria:

18 to 80 years of age Meet the diagnostic criteria Receive invasive mechanical ventilation within 48 hours

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Exclusion Criteria:

Patients with those disease will be excluded ： chronic obstructive pulmonary disease Pulmonary embolism Chronic heart failure Idiopathic pulmonary fibrosis Pulmonary hypertension Pregnant women will be excluded too.

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+Locations (1)

Facility	City	Country	Status
Affiliated Hospital of QingHai University	Xining, Qinghai	China	Recruiting

+Publications

Results publication: Zhu P, Zhu J, Tong S, She X, Qi Z, Xu Q, Shi Z, Si L, Hou M, Gan G, Pan C. Clinical characteristics of patients with a risk of pulmonary artery hypertension secondary to ARDS in a high-altitude area. BMJ Open Respir Res. 2023 Jul;10(1):e001475. doi: 10.1136/bmjresp-2022-001475. PMID 37524522

+Investigators

Chun Pan, MD, Principal investigator, Qinghai University

My Notes

Public

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