Methods of Confirmation of Brain Death

Organ donation is possible in the Czech Republic only after meeting the legislative requirements. These require confirmation of brain death by one of the statutory methods before organ harvesting. The use of these methods in clinical practice has not yet been described.The aim of this retrospective observational study is to describe the use of these methods in the real clinical practice of the transplant program in the Czech Republic, taking into account the legislation of other European countries.

Primary outcomes

• Angiography [within 24 hours after the onset of signs of brain death]: Cerebral panangiography
• Brainstem auditory evoked potentials [within 24 hours after the onset of signs of brain death]: Brainstem auditory evoked potentials
• Brain scintigraphy [within 24 hours after the onset of signs of brain death]: Brain scintigraphy
• Cerebral computed tomography angiography [within 24 hours after the onset of signs of brain death]: Cerebral computed tomography angiography
• Transcranial Doppler ultrasonography [within 24 hours after the onset of signs of brain death]: Transcranial Doppler ultrasonography

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* age ≥18 years
* organ donor

Exclusion Criteria:

* age under 18 years

• Roman Gal, M.D., Ph.D., Study chair, Brno University Hospital