Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery

NCT04670224 — Not applicable, Active not recruiting, 286 participants, Centre Hospitalier Universitaire, Amiens
ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  
RegistryNCT04670224, acronym QLB
StatusActive not recruiting
PhaseNot applicable
Study typeInterventional; randomized, parallel, masking: none, treatment
Enrollment286 (Estimated)
SponsorCentre Hospitalier Universitaire, Amiens (Other)
ConditionsQuadratus Lumborum Block, Abdominoplasty, Analgesia, Locoregional Anesthesia
InterventionsQLB anesthesia, Intravenous anesthesia without QLB (Other)
Datesstart 2021-03-16, primary completion 2025-12-01 (estimated), completion 2026-01-01 (estimated), first posted 2020-12-17, last updated 2025-05-29
Locations1 site in France

Related Papers Related Patents Related Grants Related Experts
All trials for Quadratus Lumborum Block All trials for Abdominoplasty All trials of QLB anesthesia All trials of Intravenous anesthesia without QLB

-Summary

Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive … Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications delay post-operative recovery. Defined in the 1990s by Professor Henry Kehlet's Danish team, rapid rehabilitation after planned surgery is an approach to overall patient care that aims to rapidly restore previous physical and mental capacities and thus significantly reduce mortality and morbidity. Pain management is at the heart of this program and local anesthesia techniques are at the heart of early rehabilitation programs.

Described for just over a decade, Quadratus Lumborum Block (QLB) have shown their effectiveness for analgesia in abdominal, or orthopedic, or obstetrical surgery. Considering the anatomical territory concerned, this locoregional anesthesia technique seems to be very interesting in abdominoplasty to allow early rehabilitation of the patient.

Expand all sections  ·  Collapse all

+Arms and interventions

ArmTypeInterventionsDescription
QLB techniqueExperimentalOther: QLB anesthesia
Intravenous anesthesia without QLBActive comparatorOther: Intravenous anesthesia without QLB
  • QLB anesthesia (Other): The QLB is a bilateral locoregional anesthesia technique, performed after surgery, under general anesthesia and in right and then left lateral decubitus.
  • Intravenous anesthesia without QLB (Other): only intravenous anesthesia

+Outcome measures

Primary outcomes

  • Variation from baseline of morphine consumption [24 hours after surgery]

Secondary outcomes

  • Variation from baseline of morphine consumption [1 hour after surgery]
  • Variation from baseline of morphine consumption [2 hours after surgery]
  • Variation from baseline of morphine consumption [48 hours after surgery]

+Eligibility

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Adult patients admitted for programmed dermo-lipectomy surgery with or without associated liposuction.

Exclusion Criteria:

* Pregnant woman
* Patient under 18 years of age
* Subject under guardianship or curators
* Patient allergic to local anesthetics
* Infection at the puncture sites
* Patient on morphine analgesic over the long term
* Patient on antidepressants for neuropathic pain.

+Locations (1)

FacilityCityCountryStatus
BARAmiensFrance