Oral D Mannose in the Prevention and Treatment of Recurrent Urinary Tract Infections: a Systematic Review
| Registry | NCT03790254, acronym mannoseRUTIs |
|---|---|
| Status | Completed |
| Study type | Observational |
| Enrollment | 500 (Actual) |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia (Other) |
| Conditions | Recurrent Urinary Tract Infections, Antibiotic Prophylaxis, Antibiotic Resistance |
| Interventions | systematic review (Other) |
| Dates | start 2010-01-01, primary completion 2018-12-20, completion 2018-12-25, first posted 2018-12-31, last updated 2018-12-31 |
| Locations | 1 site in Italy |
Related Papers Related Patents Related Grants Related Experts
All trials for Recurrent Urinary Tract Infections All trials for Antibiotic Prophylaxis All trials of systematic review
The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.
A comprehensive systematic MEDLINE, Embase, Cochrane search was performed for English language reports published before December 2018 using the term "recurrent urinary tract infections and d mannose." We searched Medline, Embase, and the Cochrane Register of Controlled Trials since January 2010 to December 2018. Eligible studies did not include non-oral therapy, local (vaginal) treatment in women with RUTIs.
Study eligibility criteria- We identified eligible original articles. The heterogeneity of the available studies, their different rationale and aim, the assumption of d mannose for prophylaxis or treatment of recurrent UTIs need to be taken into account.
Sex: All, ages: 18 Years to 90 Years
Inclusion Criteria: recurrent urinary tract infections (RUTIs) Exclusion Criteria: Upper urinary tract infections, severe clinical symptoms, fever > 37,5 with lumbar pain
| Facility | City | Country | Status |
|---|---|---|---|
| Urology Department Fondazione IRCCS Policlinico San Matteo | Pavia | Italy |