The Effect of Wild Blueberry Consumption on Glucose Regulation in Healthy Adults

Healthy men and women (ages 21 - 65 years) were recruited to take part in a randomized, placebo controlled crossover design study. Subjects were screened to determine their health status (e.g. height, weight, body mass index, blood pressure and medical history). Subjects were randomly assigned to a sequence of two treatments with two study periods. The treatments are frozen wild blueberries and a placebo developed to match calories and fiber of the frozen wild blueberries. The subjects were asked to avoid high polyphenol foods in their typical diet for 7 days and consume one of the two treatments as a dietary intervention. After the seventh day subjects consumed a test meal along with either the wild blueberry or placebo. Blood was collected to determine glucose and satiety hormone levels.

• Blueberry (Other): Blueberry - 150 grams wild blueberries (whole fruit)
• Placebo (Other): Placebo - matched for calories and fiber

Primary outcomes

• Glucose (mmol/L) [Change from baseline 0 hours and 2 hours]: Plasma glucose

Sex: All, ages: 21 Years to 65 Years, accepts healthy volunteers

Inclusion Criteria:

* Male or female

Exclusion Criteria:

* BMI < 20 and > 30 kg/m²
* Pregnant women or women who plan on becoming pregnant during the study
* Postpartum women
* Lactating women
* Diabetes Mellitus
* Kidney disease
* Liver disease
* GI Disease
* Certain cancers
* Smokers
* Blueberry allergies

• Katherine Gottschall-Pass, PhD, Principal investigator, University of Prince Edward Island