Fundus Autofluorescence After Vitrectomy for Epiretinal Membrane

NCT02628158 — Completed, 91 participants, Kyorin University

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Correlation of Postoperative Vision and Fundus Autofluorescence After Vitrectomy for Epiretinal Membrane

Registry	NCT02628158
Status	Completed
Study type	Observational
Enrollment	91 (Actual)
Sponsor	Kyorin University (Other)
Conditions	Epiretinal Membrane
Interventions	Vitrectomy with internal limiting membrane removal (Procedure)
Dates	start 2013-04-01, primary completion 2015-04-01, completion 2015-10-01, first posted 2015-12-11, last updated 2015-12-11
Locations	1 site in Japan

-Summary

Fundus autofluorescence (FAF) at the macula originates from hyperfluorescence from retinal pigment epithelium (RPE) and blockage of hyperfluorescence by macular pigment. Investigators evaluate whether presence of FAF may correlate to the postoperative visual outcome for epiretinal membrane.

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+Detailed description

92 eyes with epiretinal membrane were performed vitreous surgery, epiretinal membrane removal and internal limiting membrane (ILM) peeling. Presence of hyperfluorescence in FAF at the macular area and best-corrected visual acuity (BCVA) was evaluated preoperatively and at postoperative 1, 3, and 6 months with ultra-wide angle imaging.

+Arms and interventions

Vitrectomy with internal limiting membrane removal (Procedure): Vitrectomy with removal of epiretinal membrane and internal limiting membrane

+Outcome measures

Primary outcomes

Visual acuity before and after surgery [Changes from baseline to 1, 3, 6 months]: Vision

Secondary outcomes

Presence of fluids autofluorescence at the macular area [Changes from baseline up to 6 months]: Fundus autofluorescence

+Eligibility

ages: 20 Years to 90 Years

Inclusion Criteria:

* The inclusion criteria were patients who underwent vitrectomy and internal limiting membrane removal for epiretinal membrane and had followed for more than 6 months.

Exclusion Criteria:

* The patients with follow-up less than 6 months.

+Locations (1)

Facility	City	Country	Status
Kyorin Eye Center	Mitaka, Tokyo	Japan

+Investigators

Makoto Inoue, MD, Principal investigator, Kyorin Eye Center