Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy: Analysis of Risk Factors and Association With Genetic Polymorphisms

NCT01510496 — Completed, 3979 participants, Fundacion IMIM
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Transition From Acute to Chronic Pain After Inguinal Hernia, Hysterectomy and Thoracotomy : Analysis of Risk Factors and Association With Genetic Polymorphisms

RegistryNCT01510496
StatusCompleted
Study typeObservational
Enrollment3979 (Actual)
SponsorFundacion IMIM (Other)
ConditionsChronic Postoperative Pain
InterventionsInguinal herniorraphy., Hysterectomy., Thoracotomy . (Procedure)
Datesstart 2009-01-01, primary completion 2012-12-01, completion 2014-07-01, first posted 2012-01-16, last updated 2015-12-30
Locations26 sites in Spain

Related Papers Related Patents Related Grants Related Experts
All trials for Chronic Postoperative Pain All trials of Inguinal herniorraphy. All trials of Hysterectomy.

-Summary

The treatment of postoperative pain continues to be inadequate in the investigators practice setting.

Inadequate pain treatment not only contributes to postoperative complications in the short term but can also be a factor that favors the development of chronic postoperative pain and diminishes long-term quality of life. Risk factors that can lead to a transition to chronic pain need to be analyzed.

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+Arms and interventions

ArmTypeInterventionsDescription
Patients who had inguinal herniorraphy.Procedure: Inguinal herniorraphy.
Patients who had hysterectomy.Procedure: Hysterectomy.
Patients who had thoracotomy.Procedure: Thoracotomy .
  • Inguinal herniorraphy. (Procedure): Inguinal herniorraphy (non laparoscopic).
  • Hysterectomy. (Procedure): Hysterectomy: Vaginal and abdominal.
  • Thoracotomy . (Procedure): Thoracotomy (non laparoscopic).

+Outcome measures

Primary outcomes

  • Evaluation of chronic postsurgical pain. [After 3 and 12 months of surgery.]: After 3 months a physical examination will take place and after 12 months a follow-up will be reported by phone.

Secondary outcomes

  • Predictive factors of chronic postsurgical pain. [After 3 and 12 months of surgery.]: Preoperative (psychological factors, preoperative pain, pharmacologic treatment) intraoperative (surgical technic, type of anaestesia) and postoperative(posoperative pain, surgical complications and treatment of postoperative pain).

+Eligibility

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Patients with given inform consent, aged mor than 18 years, who undergo scheduled surgery of one of the following types: inguinal hernia (men), hysterectomy, thoracotomy (men).

Exclusion Criteria:

* Patients aged less than 18 years,
* Patients requiring reoperation because of surgical complications.

+Locations (26)

FacilityCityCountryStatus
Hospital Municipal de BadalonaBadalona, BarcelonaSpain
Hospital Universitari Germans Trias i PujolBadalona, BarcelonaSpain
Hospital del MarBarcelona, BarcelonaSpain
Hospital de l'EsperançaBarcelona, BarcelonaSpain
Hospital de la Santa Creu i Sant PauBarcelona, BarcelonaSpain
Hospital Sagrat CorBarcelona, BarcelonaSpain
Hospital Universitari Vall d'HebronBarcelona, BarcelonaSpain
Hospital Clínic i Provincial de BarcelonaBarcelona, BarcelonaSpain
Hospital del Sant BoiBarcelona, BarcelonaSpain
Hospital de San BernabéBerga, BarcelonaSpain
Hospital de GranollersGranollers, BarcelonaSpain
Hospital Universitari de BellvitgeL'Hospitalet de Llobregat, BarcelonaSpain
Hospital General de ManresaManresa, BarcelonaSpain
Hospital de MataroMataró, BarcelonaSpain
Hospital Parc TauliSabadell, BarcelonaSpain
Hospital Mutua de TerrassaTerrassa, BarcelonaSpain
Hospital Universitari Mutua de TerrassaTerrassa, BarcelonaSpain
Hospital de ViladecansViladecans, BarcelonaSpain
Hospital Universitari Doctor Josep Trueta de GironaGirona, GironaSpain
Hospital de Santa CaterinaSalt, GironaSpain
Hospital Santa MariaLleida, LleidaSpain
Hospital Sant Joan de ReusReus, TarragonaSpain
Hospital Clínico de ValenciaValencia, ValenciaSpain
Hospital General Universitario de ValenciaValencia, ValenciaSpain
Hospital Universitari de la FeValencia, ValenciaSpain
Hospital Lluís Alcanyís de XàtivaXàtiva, ValènciaSpain

+Publications

  • Results publication: Bande D, Molto L, Pereira JA, Montes A. Chronic pain after groin hernia repair: pain characteristics and impact on quality of life. BMC Surg. 2020 Jul 6;20(1):147. doi: 10.1186/s12893-020-00805-9. PMID 32631293
  • Results publication: Montes A, Roca G, Sabate S, Lao JI, Navarro A, Cantillo J, Canet J; GENDOLCAT Study Group. Genetic and Clinical Factors Associated with Chronic Postsurgical Pain after Hernia Repair, Hysterectomy, and Thoracotomy: A Two-year Multicenter Cohort Study. Anesthesiology. 2015 May;122(5):1123-41. doi: 10.1097/ALN.0000000000000611. PMID 25985024