Identification of New Biomarkers of Drug Induced Liver Injury
| Registry | NCT01000766 |
|---|---|
| Status | Completed |
| Study type | Observational |
| Enrollment | 25 (Actual) |
| Sponsor | University of North Carolina, Chapel Hill (Other) |
| Conditions | Drug Induced Liver Injury |
| Dates | start 2009-09-01, primary completion 2013-12-01, completion 2013-12-01, first posted 2009-10-23, last updated 2017-04-18 |
| Locations | 1 site in United States |
Related Papers Related Patents Related Grants Related Experts
All trials for Drug Induced Liver Injury
The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver.
Our hypothesis is that there are liver-specific particles, called mRNA, that are identifiable in a person's blood sample during liver injury caused by some drugs. The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver, perhaps early in the process before significant injury or illness have occurred.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Acute drug-induced liver injury |
Sex: All, ages: 18 Years to 80 Years
Inclusion Criteria: * ALT > 200 IU/L at presentation to UNC Hospitals * Drug induced liver injury considered likely by admitting medical staff
| Facility | City | Country | Status |
|---|---|---|---|
| University of North Carolina | Chapel Hill, North Carolina | United States |