Cell Behavior Papers of the Week

Immunohistological analysis revealed that neurofilament heavy chain (NFH) immunoreactivity increased with age and correlated significantly with effective Young’s modulus, while glial fibrillary acidic protein (GFAP) immunoreactivity, despite increasing with age, did not correlate with stiffness, suggesting that neuron maturation contributes to age-dependent stiffening.

We study the run-tumble motion of a single autochemotactic agent that secretes and senses chemical cues using a reinforcement learning (RL) framework.

Drawing on 98 studies published between January 2015 and February 2026, this review examines the connections between mechanical stimulation, EV remodeling and biological outcomes.

Here, we investigated the role of QSOX1 in tumor–stromal interactions in lung adenocarcinoma (LUAD).

This work provides a system-theoretic formulation and analysis of Extended Cellular Potts Models (ECPMs) that explicitly couple tumor dynamics with ECM degradation.

Virtual tissue models link observations to mechanistic hypotheses, but building them demands expertise in biology, mathematics and programming.

We analyzed public bulk and single-cell transcriptomic datasets and performed functional experiments.

Here, we compared peripheral blood mononuclear cells (PBMCs) from control donors or individuals with PD in human induced pluripotent stem cell (iPSC)-derived BBB models to determine how static and dynamic BBB systems influence immune cell behavior.

We introduce a unified optimal transport framework for the Immersed Boundary (IB) electrodiffusion active pump model.

Cell density, measured in the HE series, was reduced at every dose to 67–86% of control across the seven doses (mean 76%) and in every quarter.

Although some vascularization studies using TVHs have been conducted, and significant progress has been made, this emerging field lacks a systematic summary. Therefore, this review summarizes the recent advances of TVHs in vascularization, including the three major strategies for precisely controlling hydrogel viscoelasticity, the influence of hydrogel viscoelasticity on vascular cell fate, and the application of hydrogel viscoelasticity in regulating blood vessel formation.

Moreover, CGRP can impair antibacterial defense in some infection models while supporting cutaneous antifungal immunity, and thrombospondin-1 has vascular effects that differ from its clearance-promoting activities. This Mini Review critically integrates these findings with recent CGRP delivery studies, distinguishing evidence from human tissue, diabetic wound models, acute injury, and infection.