Topics / Infectious Diseases
Weekly issue
Infectious Diseases Papers of the Week
The 20 most important new Infectious Diseases papers of the past week, ranked by potential impact. A new issue comes out every Monday, covering the previous Monday-to-Sunday week.
- 1Undertreatment of Cervical Precancer Among Screen-Positive Women Living with HIV in Kenya
We described screening results and the post-screening management cascade among WLWH receiving HIV care in Nairobi, Kenya.
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- 4Carbapenemase-Producing Carbapenem-Resistant Enterobacterales Among Children in The United States, 2019-2024
We analyzed CRE clinical isolates from patients <18 years submitted to CDC's Antimicrobial Resistance Laboratory Network from January 2019 through December 2024.
- 5The Contribution of Population Genetics to The Epidemiological Tracing of Pathogenic Bacteria: The Predominant Clonal Evolution Model
This article aims to present the specific contribution of population genetics and evolutionary genetics to the molecular tracing of epidemiological routes in bacteria pathogenic to humans and animals.
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Follow this category- 6Inhibiting The MiR-511-3p/PTCH1/Hedgehog Axis Alleviates Sepsis-Induced Systemic Inflammation and Acute Liver Injury
Because patched 1 (PTCH1), a validated target of miR-511-3p, serves as a key negative regulator of hedgehog (HH) signaling, we hypothesized that miR-511-3p promotes inflammatory responses during sepsis by suppressing PTCH1 expression and consequently activating HH signaling.
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- 8The Variance Problem in Human Oversight of Clinical AI: Measuring Four Safeguards Across Nine Reviewers on A Nurse-Facing Deterioration Testbed
We introduce a controlled measurement instrument for evaluating four candidate safeguards: an ordering constraint on when model advice is revealed, the content disclosed to the reviewer, a recorded disposition with a closed reason vocabulary, and aggregate monitoring of the resulting oversight log.
- 9PEDV NSP5 Promotes Immune Evasion By Recruiting TRIM28 to Degrade DDX3X
In this study, reverse transcription quantitative PCR was used to examine the gene expression changes of 15 DEAD-box family members in the intestinal tissues of one-month-old PEDV-infected piglets.
- 10Integrated Risk-resource Assessment and Automated Decision-making for Sewage Sludge Management in Megacities: Development and Implementation of The IRRSS Framework
This study provides a transferable, data-driven framework that transforms sludge from a waste burden into a managed resource stream, bridging the gap between complex statistical analysis and practical engineering decision-making.
- 11Adenovirus-Derived Virus-Like Particles Enable Rapid Encapsulation and Delivery of Functional Antigen Cargo
Here, we developed an adenovirus-derived virus-like particle (Ad5VLP) platform that enables modular incorporation of antigen cargo without reconstruction of a complete antigen-encoding adenoviral genome.
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- 13Rmf , A Conserved Ribosome Hibernation Marker of Convergent Dormancy in Experimentally Evolved Escherichia Coli
We used multiple public data sets to test whether divergent lineages converge on a shared physiological endpoint.
- 14Microbiota-dependent Citrulline Metabolism Alleviates Sepsis By Activating The Aryl Hydrocarbon Receptor/IL-22 Pathway to Restore Intestinal Homeostasis
This study investigated whether citrulline ameliorates sepsis-associated immune inflammation and intestinal barrier injury by modulating gut microbiota metabolites.
- 15A Human Gut-associated Picobirnavirus Establishes The Picobirnaviridae As The Third Clade of RNA Bacteriophages
Although PBVs have been assumed to infect vertebrate hosts, there is neither direct evidence for this nor any culture system to propagate PBVs. Here we demonstrate that a PBV infects bacteria and is therefore an RNA phage.
- 16In-Hospital Outcomes and Mortality After Revascularization for Chronic Mesenteric Ischemia By Maintenance Dialysis Status: A National Inpatient Sample Analysis, 2006-2020
We analyzed adult CMI-coded hospitalizations undergoing endovascular or open revascularization in the 2006-2020 National Inpatient Sample.
- 17Identification of Vibrio Cholerae Proteins That Bind 3',3'-cyclic Guanosine Adenine Dinucleotide
To identify additional 3',3'-cGAMP-binding proteins, we performed a 3',3'-cGAMP-binding screen of the El Tor ORFeome.
- 18Interpreting High-Sensitivity Cardiac Troponin in Clinical Practice and Emerging Directions: Detection Is No Longer Diagnosis
We provide explicit bedside guidance for the situations that clinicians find most difficult, including suspected secondary MI, the observe zone, and troponin elevation without a dynamic pattern.
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- 20Antimicrobial Peptides Derived from Nemuri Induce Ribosomal Condensation to Inhibit Translation
Here, we identify intrinsically disordered antimicrobial peptides, generated from the Drosophila sleep-inducing protein Nemuri, that inhibit bacterial growth by targeting ribosomal organization.