Databases Papers of the Week

Introduction This scoping review aims to evaluate artificial intelligence (AI), particularly deep learning, for predicting periodontal risks in orthodontic patients and to identify methodological gaps limiting clinical translation.

We performed a systematic review and content analysis of CPG to assess the impact of databases searched and publication language on the quantity, quality, and content of recommendations identified for pediatric FN.

This review evaluates biodiversity patterns, ecological functions, environmental pressures, and conservation approaches associated with Acer forests.

Introduction The present study aimed to perform a systematic review and meta-analysis to evaluate the potential therapeutic effects and underlying mechanisms of Escin and its nanoparticle formulations in cancer based on preclinical studies.

STATA 15.0 and Review Manager 5.4 software were used, and random-effects models were employed with pooled hazard ratios (HR) and their 95% confidence intervals (CI) to assess the prognostic value of SIRI.

The single-sample gene set enrichment analysis (ssGSEA) algorithm was used to estimate immune infiltrates.

Of 59 studies selected for inclusion in the review, 57 focused primarily on asthma/lung disease, 6 variably reported on poorly described allergy outcomes, and 2 reported on atopic dermatitis.

Digital tools are increasingly integrated into patient engagement (PE) in chronic disease management, yet findings remain fragmented across populations, modalities, and outcome definitions. The aim of this umbrella review was to systematically review evidence on the effectiveness of Digital Health Interventions (DHIs) to enhance PE and related health outcomes.

This study comprehensively investigated the expression pattern, clinical significance, and potential molecular mechanisms of ABO in BRCA.

Natural Nrf2 modulators and miRNA-based therapeutics (mimics/inhibitors) represent promising strategies to restore redox balance, suppress tumor progression, and overcome multidrug resistance. This review highlights the bidirectional crosstalk between Nrf2 and miRNAs and discusses its therapeutic potential in cancer.

Sports offer substantial physical and psychosocial benefits, yet sports organizations face an alarming, age-related decline in adolescent retention rates. This systematic review explored the determinants, interpersonal/structural motives, and career indicators that explain the sport dropout process, synthesizing the core theoretical frameworks underpinning athletic persistence.

This study aims to systematically review and synthesise evidence on DT-enabled H&S management during the construction stage.

Despite growing concern regarding the environmental impacts of pharmaceutical manufacturing, environmental sustainability is not a primary objective of conventional good manufacturing practice (GMP) frameworks, and cleaner production principles remain unevenly integrated into pharmaceutical manufacturing regulation and practice. This scoping review, conducted following JBI methodology and reported in accordance with PRISMA-ScR, mapped peer-reviewed and gray literature published from 2000 through July 2025 on environmental sustainability and climate change mitigation in pharmaceutical manufacturing.

The research articles published in the English language between January 1928 and June 2026 were included.

The review examined trends in the evidence base and synthesized objectively measured improvements and null/negative effects.

Results We included 232 publications encompassing 1133 unique outcomes across 12 condition categories and 559792 participants.

Methods: This review was conducted in line with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) guidelines.

We made scoping review to better identify the use of TA for managing severe irAEs.