4 recruiting, 1 active not recruiting, 1 suspended. 5 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Recruiting 3, Active not recruiting 1, Suspended 1 |
| Early Phase 1 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Imaging Study of [89Zr]DFO-YS5 for Cancer Detection [89Zr]DFO-YS5, Positron Emission Tomography (PET)-Computerized tomography (CT) - Bladder Cancer, Nerve Sheath Tumor | Phase 1 | Recruiting | Robert Flavell, MD, PhD | 40 | 2026-06-15 | 2026-10-01 |
| PET [89Zr]DFO-starPEG in Solid Tumors 89-zr-dfo-star polyethylene glycol (StarPEG), Whole Body Positron Emission Tomography (PET), Specimen Collection - Solid Tumor, Solid Carcinoma | Phase 1 | Recruiting | Robert Flavell, MD, PhD | 13 | 2025-06-02 | 2026-06-05 |
| Magnetic Resonance (MR) Imaging With Hyperpolarized Bicarbonate (13C) to Measure Tissue pH in Prostate Cancer Hyperpolarized Bicarbonate (13C), Magnetic Resonance imaging - Prostate Cancer, Localized Prostate Carcinoma | Early Phase 1 | Recruiting | Robert Flavell, MD, PhD | 10 | 2023-07-06 | 2026-10-13 |
| Imaging Study of [89Zr]DFO-YS5 for Detecting CD46 Positive Malignancy in Multiple Myeloma Zirconium Zr 89-DFO-YS5, Positron Emission Tomography / Computed Tomography (PET/CT), Positron Emission Tomography / Magnetic Resonance Imaging (PET/MRI) - Multiple Myeloma, Plasma Cell Myeloma | Phase 1 | Recruiting | Robert Flavell, MD, PhD | 20 | 2023-06-16 | 2026-09-16 |
| PET Imaging Study of 89Zr-DFO-YS5 in Men With Prostate Cancer 89Zr-DFO-YS5, YS5 antibody, Positron Emission Tomography (PET)/Computerized tomography (CT) - Prostate Cancer, Metastatic Castration-resistant Prostate Cancer | Phase 1 | Active not recruiting | Robert Flavell, MD, PhD | 30 | 2022-03-18 | 2026-03-17 |
| Zr-89 Cimzia PET Imaging Rheumatoid Arthritis 89Zr-DFO-CZP - Rheumatoid Arthritis | Phase 1 | Suspended | Robert Flavell, MD, PhD | 10 | 2018-10-01 | 2026-05-04 |
Prostatic Neoplasms (2) · Arthritis, Rheumatoid (1) · Multiple Myeloma (1) · Nerve Sheath Neoplasms (1) · Pyloric Stenosis, Hypertrophic (1) · Urinary Bladder Neoplasms (1)
Magnetic Resonance Spectroscopy (4) · Fluorodeoxyglucose F18 (1) · Specimen Handling (1) · acetyl-glycyl-asparagyl-glutaminyl-glutamyl-glutaminyl-valyl-seryl-prolyl-leucyl-threonyl-leucyl-leucyl-lysyl-lysyl-tryptophyl-cysteinyl-Alexa Fluoro 680 C2C2-maleimide conjugate (1)
United States (6)
R01CA266666 (1), R01CA271606 (1)