6 completed, 1 recruiting. 5 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 4, Recruiting 1 |
| Phase 1 | 4 | Completed 3, Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy IRL757, Placebo - PARKINSON DISEASE (Disorder), Apathy | Phase 1 / Phase 2 | Recruiting | Integrative Research Laboratories AB | 75 | 2026-02-18 | 2026-09-03 |
| Phase I Trial Evaluating the Pharmacokinetics of Single Ascending Oral Doses of IRL757 in Healthy Elderly Volunteers IRL757 - Not Applicable as This is a Mass Balance/Pharmacokinetic Study Performed in Healthy Subjects, Apathy | Phase 1 | Completed | Integrative Research Laboratories AB | 12 | 2024-09-23 | 2026-02-05 |
| First-In-Human (FIH) Trial Evaluating the Safety and Tolerability of Single and Multiple Ascending Oral Doses of IRL757 in Healthy Volunteers IRL757, Placebo - Not Determined | Phase 1 | Completed | Integrative Research Laboratories AB | 82 | 2024-05-16 | 2026-05-15 |
| A Clinical Study Evaluating Efficacy of Pirepemat on Falls Frequency in Patients With Parkinson's Disease (PD) Pirepemat, Placebo - Parkinson Disease | Phase 2 | Completed | Integrative Research Laboratories AB | 104 | 2022-06-15 | 2026-07-09 |
| A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia Mesdopetam, Placebo - Parkinson Disease | Phase 2 | Completed | Integrative Research Laboratories AB | 155 | 2020-10-29 | 2024-03-06 |
| Efficacy and Tolerability of IRL790 in Parkinson's Disease Dyskinesia Mesdopetam (IRL790) - Parkinson Disease | Phase 2 | Completed | Integrative Research Laboratories AB | 75 | 2018-04-12 | 2022-03-31 |
| A Clinical Study of IRL790 in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia IRL790, Placebo - Parkinson Disease | Phase 1 / Phase 2 | Completed | Integrative Research Laboratories AB | 15 | 2016-11-08 | 2018-05-21 |
Parkinson Disease (5) · Lethargy (2)
mesdopetam (3)
Sweden (4) · Poland (3) · France (2) · Germany (2) · Spain (2) · Bulgaria (1) · Israel (1) · Italy (1) · Netherlands (1) · Serbia (1) · United Kingdom (1) · United States (1)
Joakim Tedroff (2) · Camille Carroll, MD (1) · Per Svenningsson, MD, PhD (1)