2 completed, 2 terminated, 1 active not recruiting, 1 recruiting. 2 Phase 3, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 1 | Active not recruiting 1 |
| Phase 4 | 1 | Recruiting 1 |
Follow Amryt Pharma: new trials by email
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Open-label Study to Evaluate Metreleptin in Children Under 6 Years of Age With Generalised Lipodystrophy Metreleptin - Generalized Lipodystrophy | Phase 3 | Terminated | Amryt Pharma | 1 | 2025-05-23 | 2026-07-22 |
| Open-label Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy Metreleptin - Partial Lipodystrophy | Phase 4 | Recruiting | Amryt Pharma | 12 | 2024-02-08 | 2025-07-03 |
| Evaluation of Safety and Efficiency of Metreleptin Treatment for Patients With Multiple Symmetric Lipomatosis (MSL) Metreleptin - Lipomatosis, Multiple Symmetrical | Phase 2 | Active not recruiting | University of Michigan | 4 | 2023-08-01 | 2025-06-12 |
| Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH) Lomitapide - Homozygous Familial Hypercholesterolaemia (HoFH) | Phase 3 | Completed | Amryt Pharma | 46 | 2020-12-14 | 2025-08-27 |
| Global Lomitapide Pregnancy Exposure Registry lomitapide - Pregnancy | Terminated | Amryt Pharma | 5 | 2014-10-01 | 2022-12-16 | |
| LOWER: Lomitapide Observational Worldwide Evaluation Registry Lomitapide - Homozygous Familial Hypercholesterolemia | Completed | Amryt Pharma | 260 | 2014-03-18 | 2026-05-12 |
Homozygous Familial Hypercholesterolemia (2) · Lipodystrophy, Congenital Generalized (1) · Lipodystrophy, Partial, Acquired (1) · Lipomatosis, Multiple Symmetrical (1)
BMS201038 (3) · metreleptin (3)
Germany (4) · Italy (4) · France (3) · United Kingdom (2) · United States (2) · Argentina (1) · Belgium (1) · Canada (1) · Greece (1) · Israel (1) · Netherlands (1) · Saudi Arabia (1) · Spain (1) · Tunisia (1)
Elif Oral (1) · Janet Boylan (1) · Sallyann O'Brien (1)