zanolimumab: Clinical Trials

6 trials of zanolimumab, newest first

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3 completed, 3 terminated. 5 Phase 2, 3 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 25Completed 3, Terminated 2
Phase 33Terminated 2, Completed 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer
Zanolimumab, Aldesleukin - Metastatic Melanoma, Metastatic Renal Cancer
Phase 2TerminatedNational Cancer Institute (NCI)92010-06-012015-10-28
HuMax-CD4 in Non-Cutaneous T-Cell Lymphoma
HuMax-CD4 - T Cell Lymphoma
Phase 2 / Phase 3CompletedEmergent BioSolutions212005-08-012024-03-18
Study of Human Monoclonal Antibody to Treat Mycosis Fungoides and Sezary Syndrome
HuMax-CD4 (zanolimumab) - Mycosis Fungoides, Sezary Syndrome
Phase 3TerminatedEmergent Product Development Seattle LLC762005-07-012012-07-26
Clinical Trial of HuMax-CD4, a New Drug to Treat Advanced Stage T-Cell Lymphoma in the Skin.
HuMax-CD4 - Cutaneous T-Cell Lymphoma
Phase 2CompletedGenmab222003-05-272023-04-28
Clinical Trial of HuMax-CD4, a New Drug to Treat Early Stage T-Cell Lymphoma in the Skin.
HuMax-CD4 - Cutaneous T-Cell Lymphoma
Phase 2CompletedGenmab252003-04-302023-05-18
Trial With HuMax-CD4 in Participants With Rheumatoid Arthritis (RA) Failing Treatment With Methotrexate (MTX) and a TNF-alpha Blocker
HuMax-CD4, Placebo, Humax-CD4 - Rheumatoid Arthritis
Phase 2 / Phase 3TerminatedGenmab832002-03-042023-04-28

Conditions studied

Lymphoma, T-Cell, Cutaneous (3)  ·  Mycosis Fungoides (3)  ·  Sezary Syndrome (3)  ·  Lymphoma (2)  ·  Skin Neoplasms (2)  ·  Arthritis, Rheumatoid (1)  ·  Kidney Neoplasms (1)  ·  Lymphoma, T-Cell (1)  ·  Melanoma (1)

Sponsors

Genmab (3)  ·  Emergent BioSolutions (1)  ·  Emergent Product Development Seattle LLC (1)  ·  National Cancer Institute (NCI) (1)

Countries

United States (5)  ·  Germany (2)  ·  Canada (1)  ·  France (1)  ·  Italy (1)  ·  Spain (1)  ·  Sweden (1)  ·  United Kingdom (1)

Top investigators

Abhay Patki, PhD (1)  ·  David S Schrump, M.D. (1)