1 completed, 1 recruiting. 2 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow WVE-006: new trials by email Literature Review of WVE-006 trials Research Report on WVE-006
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD WVE-006 - Alpha-1 Antitrypsin Deficiency | Phase 1 / Phase 2 | Recruiting | Wave Life Sciences USA, Inc. | 48 | 2024-07-19 | 2026-10-19 |
| A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) WVE-006 - Alpha-1 Antitrypsin Deficiency (AATD) | Phase 1 | Completed | Wave Life Sciences USA, Inc. | 47 | 2023-11-14 | 2026-03-23 |
alpha 1-Antitrypsin Deficiency (2)
Wave Life Sciences USA, Inc. (2)
United Kingdom (2) · Australia (1) · Canada (1) · Finland (1) · Germany (1) · New Zealand (1)