3 completed, 3 terminated. 5 Phase 2, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Terminated 3, Completed 2 |
| Phase 1 | 3 | Terminated 2, Completed 1 |
Follow TLC 388: new trials by email Literature Review of TLC 388 trials Research Report on TLC 388
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lipotecan Based Concurrent Chemoradiotherapy in Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis Lipotecan - HepatoCellular Carcinoma, Portal Vein Tumor Thrombosis | Phase 1 / Phase 2 | Terminated | Taiwan Liposome Company | 1 | 2017-04-14 | 2018-11-06 |
| Phase II Study to Evaluate the Efficacy and Safety of TLC388 for Differentiated Neuroendocrine Carcinomas Patients TLC 388 - Neuroendocrine Carcinomas | Phase 2 | Completed | National Health Research Institutes, Taiwan | 23 | 2015-07-04 | 2019-04-03 |
| Efficacy and Safety Study of TLC388 to Advanced Hepatocellular Carcinoma Lipotecan - Hepatocellular Carcinoma | Phase 2 | Terminated | Taiwan Liposome Company | 29 | 2014-04-10 | 2019-02-26 |
| A Phase II Study to Evaluate the Efficacy and Safety of TLC388 in Advanced/Metastatic RCC Patients Lipotecan - Advanced/Metastasis Renal Cell Carcinoma | Phase 2 | Completed | Taiwan Liposome Company | 18 | 2012-11-30 | 2018-06-26 |
| A Dose-escalation Study of Lipotecan® Plus Radiotherapy in Locally Advanced Hepatocellular Carcinoma Lipotecan® (TLC388) - Carcinoma, Hepatocellular | Phase 1 / Phase 2 | Terminated | Taiwan Liposome Company | 3 | 2011-10-27 | 2018-08-21 |
| Phase I Study of Intravenous Lipotecan® (TLC388 HCl for Injection) in Patients With Advanced Solid Tumors Lipotecan - Advanced Solid Tumors | Phase 1 | Completed | Taiwan Liposome Company | 54 | 2008-09-01 | 2019-11-18 |
Carcinoma, Hepatocellular (3) · Carcinoma, Neuroendocrine (1)
Taiwan Liposome Company (5) · National Health Research Institutes, Taiwan (1)
Taiwan (6) · China (1) · United States (1)
Carl Brown, PhD (1) · Chen-Hsi Hsieh, MD (1) · Cheng-Chung Wu, MS (1) · Chia-Jui Yen, MD., PhD (1) · Chiun Hsu, MD., PhD (1) · Dr. Yvonne Shi (1) · Hui-Jen Tsai, MD., PhD (1) · Jacqueline Whang-Peng, MD (1) · Jen-Shi Chen, MD (1) · Min-Hsiung Kao (1) · Ming-Huang Chen, MD., PhD (1) · Ta-Chih Liu, MD., PhD (1) · Tsang-En Wa, MD (1) · Yee Chao, MD (1) · Yee Chao, MD., PhD (1)