4 terminated, 2 completed. 6 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Terminated 4, Completed 2 |
Follow SPR001: new trials by email Literature Review of SPR001 trials Research Report on SPR001
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens Tildacerfont, Placebo - Polycystic Ovary Syndrome | Phase 2 | Terminated | Spruce Biosciences | 27 | 2022-05-15 | 2025-10-09 |
| A Phase 2 Study to Evaluate the Safety, Efficacy and PK of Tildacerfont in Children Aged 2-17 Years With CAH Tildacerfont - Congenital Adrenal Hyperplasia, 21-OHD | Phase 2 | Terminated | Spruce Biosciences | 67 | 2021-12-10 | 2025-12-24 |
| A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH Tildacerfont/Placebo - Congenital Adrenal Hyperplasia | Phase 2 | Terminated | Spruce Biosciences | 100 | 2021-02-22 | 2025-10-01 |
| A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH Tildacerfont/Placebo - Congenital Adrenal Hyperplasia | Phase 2 | Terminated | Spruce Biosciences | 96 | 2020-08-26 | 2025-07-08 |
| Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia SPR001 - Congenital Adrenal Hyperplasia, CAH - Congenital Adrenal Hyperplasia | Phase 2 | Completed | Spruce Biosciences | 11 | 2018-09-06 | 2025-04-01 |
| Study of SPR001 in Adults With Classic Congenital Adrenal Hyperplasia SPR001 - Congenital Adrenal Hyperplasia, CAH - Congenital Adrenal Hyperplasia | Phase 2 | Completed | Spruce Biosciences | 24 | 2017-07-12 | 2025-10-22 |
Adrenal Hyperplasia, Congenital (5) · Adrenal Gland Diseases (4) · Polycystic Ovary Syndrome (1)
United States (6) · Australia (2) · Brazil (2) · Canada (2) · Estonia (2) · Germany (2) · Italy (2) · Latvia (2) · Lithuania (2) · Poland (2) · Romania (2) · South Korea (2) · Spain (2) · Sweden (2) · Turkey (Türkiye) (2)
Will Charlton, MD (2) · Kyriakie Sarafoglou, M.D (1) · Richard Auchus, MD, PhD (1) · Ron Newfield, M.D (1)