3 completed, 1 active not recruiting, 1 not yet recruiting. 3 Not applicable, 1 Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 3 |
| Phase 1 | 1 | Not yet recruiting 1 |
| Phase 2 | 1 | Not yet recruiting 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Propionates: new trials by email Literature Review of Propionates trials Research Report on Propionates
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Safety, Efficacy, and Pharmacodynamics of PLL001 in ALS Patients PLL001 or placebo daily subcutaneous injections - Amyotrophic Lateral Sclerosis, ALS | Phase 1 / Phase 2 | Not yet recruiting | PLL TX AUSTRALIA PTY LTD | 153 | 2026-04-08 | 2026-03-19 |
| Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma dupilumab, Matching Placebo, ICS/LABA - Asthma | Phase 4 | Active not recruiting | Regeneron Pharmaceuticals | 120 | 2024-08-26 | 2026-05-22 |
| Safety and Efficacy of Propionate for Reduction of LDL Cholesterol Calcium-Propionate 500mg, Placebo - Hypercholesterolemia | Not applicable | Completed | Charite University, Berlin, Germany | 62 | 2018-07-25 | 2020-09-16 |
| Investigating Optimal Propionate Delivery to the Colon Using Stable Isotope Labeling Inulin, 2.5 g of propionate, 5 g of propionate - Optimum Propionate Delivery to the Large Intestine | Not applicable | Completed | Scottish Universities Environmental Research Centre | 10 | 2014-08-01 | 2016-04-28 |
| Rectal Short Chain Fatty Acids Combinations and Substrate and Energy Metabolism Three different mixture of acetate, butyrate and propionate and palcebo - Obesity, Type 2 Diabetes | Not applicable | Completed | Maastricht University Medical Center | 12 | 2013-09-01 | 2014-10-21 |
Amyotrophic Lateral Sclerosis (1) · Asthma (1) · Diabetes Mellitus, Type 2 (1) · Hypercholesterolemia (1) · Obesity (1)
Charite University, Berlin, Germany (1) · Maastricht University Medical Center (1) · PLL TX AUSTRALIA PTY LTD (1) · Regeneron Pharmaceuticals (1) · Scottish Universities Environmental Research Centre (1)
Germany (2) · Canada (1) · Denmark (1) · Netherlands (1) · Poland (1) · Puerto Rico (1) · United Kingdom (1) · United States (1)
Arash Haghikia, PD MD (1) · Douglas Morrison, PhD (1) · Tina Soulis (1)
2023 (1)