3 completed, 2 terminated. 2 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 2 | Completed 2 |
| Phase 3 | 2 | Terminated 2 |
| Phase 1 | 1 | Completed 1 |
Follow PRM-151: new trials by email Literature Review of PRM-151 trials Research Report on PRM-151
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate Long Term Safety and Efficacy of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis PRM-151 (Zinpentraxin Alfa) - Idiopathic Pulmonary Fibrosis | Phase 3 | Terminated | Hoffmann-La Roche | 117 | 2021-08-30 | 2024-05-16 |
| A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis PRM-151 (Zinpentraxin Alfa), Placebo - Idiopathic Pulmonary Fibrosis | Phase 3 | Terminated | Hoffmann-La Roche | 665 | 2021-03-19 | 2024-04-18 |
| A Trial to Evaluate the Efficacy of PRM-151 in Subjects With Idiopathic Pulmonary Fibrosis (IPF) PRM-151, placebo - Idiopathic Pulmonary Fibrosis | Phase 2 | Completed | Hoffmann-La Roche | 117 | 2015-09-01 | 2022-05-02 |
| A Phase 1b Study of IV PRM151 in Patients With Idiopathic Pulmonary Fibrosis (IPF) PRM-151, Placebo - Idiopathic Pulmonary Fibrosis | Phase 1 | Completed | Hoffmann-La Roche | 21 | 2011-03-29 | 2022-04-20 |
| PRM-151 in the Prevention of Scarring Following Trabeculectomy PRM-151, Placebo - Glaucoma | Phase 2 | Completed | Hoffmann-La Roche | 124 | 2010-06-14 | 2022-04-28 |
Idiopathic Pulmonary Fibrosis (4) · Glaucoma (1) · Pulmonary Fibrosis (1)
Netherlands (5) · Czechia (4) · United States (4) · Belgium (3) · Germany (3) · Italy (3) · Spain (3) · Argentina (2) · Australia (2) · Canada (2) · China (2) · Denmark (2) · France (2) · Greece (2) · Hong Kong (2)
Bernt van den Blink, MD, PhD (1) · Jeffrey Edelson, MD, FRCPC, MHSc (1) · John Getsy, DMD, DO (1)
PMID 36724330, PMID 26869678, PMID 29800034, PMID 31122893, PMID 35597980, PMID 38354066, PMID 39761005
2009 (1), 2014 (1)