7 completed, 1 unknown. 4 Phase 1, 3 Not applicable, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 4 |
| Not applicable | 3 | Completed 2, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow lactisole: new trials by email Literature Review of lactisole trials Research Report on lactisole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Sweetness Intensity of a Sucrose Solution on Blood Glucose Regulation and Energy Intake Lactisole, Rebaudioside M, Sucrose - Blood Glucose, Low, Hunger | Early Phase 1 | Completed | University of Vienna | 30 | 2021-08-05 | 2023-01-26 |
| Acute Effects of the Two Alternative Sweeteners D-allulose and Erythritol on Metabolism Erythritol, Erythritol + lactisole, D-allulose - Physiological Satiation Mechanisms | Not applicable | Completed | University Hospital, Basel, Switzerland | 18 | 2019-09-01 | 2020-09-29 |
| Interactions of Human Gut Microbiota With Intestinal Sweet Taste Receptors Oral Glucose Tolerance Test (OGTT), Assessment of dietary compliance, Stool sampling - Obesity | Not applicable | Completed | AdventHealth Translational Research Institute | 102 | 2017-01-26 | 2023-02-02 |
| Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY lactisole, mixed liquid meal - Taste Disorder, Primary, Sweet | Phase 1 | Completed | University Hospital, Basel, Switzerland | 10 | 2010-06-01 | 2015-07-16 |
| The Effect of Lactisole on the Responses to Glucose Solution Lactisole - Blood Glucose, Appetite | Not applicable | Unknown | Northern Care Alliance NHS Foundation Trust | 24 | 2010-05-01 | 2010-05-12 |
| Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides lactisole - Taste Disorder, Secondary, Sweet | Phase 1 | Completed | University Hospital, Basel, Switzerland | 16 | 2010-01-01 | 2011-02-24 |
| Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY lactisole - Appetite and General Nutritional Disorders, Hormone Replacement | Phase 1 | Completed | University Hospital, Basel, Switzerland | 16 | 2009-04-01 | 2011-02-23 |
| Study of the Effect of Lactisole on the Intestinal Glucose Uptake lactisole, placebo - Healthy | Phase 1 / Phase 2 | Completed | University Ghent | 10 | 2008-03-01 | 2009-04-07 |
Taste Disorders (2) · Obesity (1)
University Hospital, Basel, Switzerland (4) · AdventHealth Translational Research Institute (1) · Northern Care Alliance NHS Foundation Trust (1) · University Ghent (1) · University of Vienna (1)
Switzerland (4) · Austria (1) · Belgium (1) · United Kingdom (1) · United States (1)
Christoph Beglinger, MD (3) · Anne Christin Meyer-Gerspach, PD, PhD (1) · Barbara Lieder, PhD (1) · David Thompson, FRCP, fMedSci, (1) · Luc Van Bortel, MD, PhD (1) · Richard Pratley, MD (1)