6 completed, 1 active not recruiting, 1 not yet recruiting. 5 Phase 1, 2 Phase 4, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 4 | 2 | Active not recruiting 1, Not yet recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow imeglimin: new trials by email Literature Review of imeglimin trials Research Report on imeglimin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy Imeglimin, Metformin 1000 mg Oral Tablet - Mitochondria, Metformin | Phase 4 | Not yet recruiting | Mansoura University | 176 | 2026-03-01 | 2026-02-27 |
| Durable Effect of Imeglimin on the Glycemic Control in Patients With Type 2 Diabetes Mellitus Imeglimin, Metformin, Vildagliptin - Diabetes Mellitus, Type 2 | Phase 4 | Active not recruiting | National Center for Global Health and Medicine, Japan | 567 | 2022-05-26 | 2026-04-09 |
| Pharmacokinetics of Imeglimin in Hepatic Impaired Subjects Imeglimin - Hepatic Impairment | Phase 1 | Completed | Poxel SA | 14 | 2018-11-06 | 2020-08-11 |
| Bioequivalence of Imeglimin Tablet Formulations Imeglimin Reference product, Imeglimin - Bioequivalence | Phase 1 | Completed | Poxel SA | 16 | 2018-09-03 | 2019-01-11 |
| Effect of Cimetidine on the PK of Imeglimin Imeglimin, Cimetidine - Healthy | Phase 1 | Completed | Poxel SA | 16 | 2018-06-19 | 2018-08-27 |
| Effect of Imeglimin on QT/QTc Intervals in Healthy Subjects Placebo, Imeglimin, Moxifloxacin - Qt Interval, Variation in | Phase 1 | Completed | Poxel SA | 55 | 2016-09-01 | 2017-02-10 |
| Safety, Tolerability and PK of Imeglimin in Japanese Volunteers Imeglimin, Placebo - Type 2 Diabetes Mellitus | Phase 1 | Completed | Poxel SA | 48 | 2015-02-01 | 2017-02-10 |
| A Study of the Efficacy and Safety of 4 Doses of Imeglimin After 24 Weeks of Treatment in Subjects With Type 2 Diabetes Imeglimin, Placebo - Type 2 Diabetes Mellitus | Phase 2 | Completed | Poxel SA | 315 | 2013-01-01 | 2015-08-13 |
Poxel SA (6) · Mansoura University (1) · National Center for Global Health and Medicine, Japan (1)
United Kingdom (4) · Egypt (1) · Germany (1) · Japan (1) · Latvia (1)
Julie Dubourg, MD (1) · Kohjiro Ueki, M.D., Ph.D. (1) · Pascale Fouqueray, MD, PhD (1) · Valdis Pirags, MD (1)
PMID 32556539, PMID 33269554, PMID 33855213
2016 (1)