ASTX029: Clinical Trials

3 trials of ASTX029, newest first

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2 completed, 1 withdrawn. 3 Phase 1, 2 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 13Completed 2, Withdrawn 1
Phase 22Completed 1, Withdrawn 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms
ASTX029, ASTX727 - Pathway Mutant Myelodysplastic Syndromes, Myelodysplastic Neoplasm
Phase 1 / Phase 2WithdrawnM.D. Anderson Cancer Center2025-01-312026-02-13
A Phase 1 Study to Evaluate the Effect of Food on Pharmacokinetics of ASTX029
ASTX029 - Healthy Volunteers
Phase 1CompletedAstex Pharmaceuticals, Inc.182020-07-232024-08-02
Study of ASTX029 in Subjects With Advanced Solid Tumors
ASTX029 - Solid Tumor, Adult
Phase 1 / Phase 2CompletedTaiho Oncology, Inc.1922018-05-072025-07-03

Conditions studied

Anemia, Refractory, with Excess of Blasts (1)  ·  Myeloproliferative Disorders (1)  ·  Neoplasms (1)

Sponsors

Astex Pharmaceuticals, Inc. (1)  ·  M.D. Anderson Cancer Center (1)  ·  Taiho Oncology, Inc. (1)

Countries

United States (3)  ·  France (1)  ·  Spain (1)  ·  United Kingdom (1)

Top investigators

Guillermo Montalban Bravo (1)

Results publications

PMID 34330842