6 completed. 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 4 |
| Phase 1 | 2 | Completed 2 |
Follow 2-Methoxyestradiol: new trials by email Literature Review of 2-Methoxyestradiol trials Research Report on 2-Methoxyestradiol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 2 Study of Panzem Nanocrystal Colloidal Dispersion (NCD) in Combination With Fixed-Dose Temozolomide to Patients With Recurrent Glioblastoma Multiforme (GBM) Panzem NCD, Temozolomide - Recurrent Glioblastoma Multiforme | Phase 2 | Completed | CASI pharmaceuticals, Inc. | 15 | 2007-04-01 | 2008-11-25 |
| A Combination Study to Determine the Safety and Efficacy of Panzem NCD With Avastin in Metastatic Carcinoid Tumors Panzem (2-methoxyestradiol) NCD, Avastin (Bevacizumab) - Carcinoid Tumor | Phase 2 | Completed | CASI pharmaceuticals, Inc. | 31 | 2006-05-01 | 2010-03-10 |
| Safety and Efficacy Study of Panzem NCD to Treat Glioblastoma Panzem Nanocrystal Colloidal Dispersion - Recurrent Glioblastoma Multiforme | Phase 2 | Completed | CASI pharmaceuticals, Inc. | 27 | 2006-01-01 | 2008-12-10 |
| 2-Methoxyestradiol in Treating Patients With Advanced Solid Tumors 2-methoxyestradiol, pharmacological study, laboratory biomarker analysis - Refractory Multiple Myeloma, Stage III Multiple Myeloma | Phase 1 | Completed | National Cancer Institute (NCI) | 60 | 2002-01-01 | 2013-01-16 |
| 2-Methoxyestradiol in Treating Patients With Advanced Solid Tumors 2-methoxyestradiol - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | National Cancer Institute (NCI) | 2001-09-01 | 2015-04-30 | |
| A Phase 2 Study With Panzem in Patients With Relapsed or Plateau Phase Multiple Myeloma 2-methoxyestradiol - Relapsed Multiple Myeloma, Plateau Phase Multiple Myeloma | Phase 2 | Completed | CASI pharmaceuticals, Inc. | 60 | 2001-03-01 | 2009-02-26 |
Glioblastoma (2) · Multiple Myeloma (2) · Carcinoid Tumor (1)
CASI pharmaceuticals, Inc. (4) · National Cancer Institute (NCI) (2)
United States (6)
Annick Desjardins, MD (1) · Charles Erlichman (1) · David A. Reardon, M.D. (1) · Matthew H. Kulke, M.D. (1) · William Dahut, MD (1)
U01CA069912 (1)