3 completed, 2 recruiting. 5 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 3, Recruiting 2 |
Follow Hepatic Impairment (HI): new trials by email Literature Review of Hepatic Impairment (HI) trials Research Report on Hepatic Impairment (HI)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetic Study of Vorolanib Tablets in Trial Participants With Hepatic Impairment vorolanib, Vorolanib - Hepatic Impairment (HI) | Phase 1 | Recruiting | Betta Pharmaceuticals Co., Ltd. | 36 | 2026-09-01 | 2026-09-09 |
| A Pharmacokinetic Study of D-2570 in Participants With Hepatic Impairment and Normal Hepatic Function D-2570 - Healthy Adult Participants, Hepatic Impairment (HI) | Phase 1 | Recruiting | InventisBio Co., Ltd | 24 | 2026-07-17 | 2026-09-23 |
| A Study to Evaluate EDG-7500 in Adults With Hepatic Impairment EDG-7500 - Hepatic Impairment (HI) | Phase 1 | Completed | Edgewise Therapeutics, Inc. | 25 | 2026-01-26 | 2026-07-31 |
| A Varegacestat Hepatic Impairment Study varegacestat - Healthy Volunteer, Hepatic Impairment (HI) | Phase 1 | Completed | Immunome, Inc. | 35 | 2025-03-07 | 2026-03-10 |
| A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015) Nemtabrutinib - Hepatic Impairment (HI) | Phase 1 | Completed | Merck Sharp & Dohme LLC | 24 | 2024-07-24 | 2026-09-02 |
Betta Pharmaceuticals Co., Ltd. (1) · Edgewise Therapeutics, Inc. (1) · Immunome, Inc. (1) · InventisBio Co., Ltd (1) · Merck Sharp & Dohme LLC (1)
United States (3) · China (2)
Huan Zhou (1)