Alopecia Totalis (AT): Clinical Trials

2 completed, 1 not yet recruiting, 1 recruiting. 2 Phase 2, 2 Phase 4.

By phase and status

Phase	Trials	Status
Phase 2	2	Completed 2
Phase 4	2	Not yet recruiting 1, Recruiting 1

Follow Alopecia Totalis (AT): new trials by email Literature Review of Alopecia Totalis (AT) trials Research Report on Alopecia Totalis (AT)

Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

Trial	Phase	Status	Sponsor	Enrollment	Start	Updated
Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA) Tofacitinib, Methotrexate - Alopecia Areata, Alopecia Totalis (AT)	Phase 4	Not yet recruiting	Hayat Abad Medical Complex, Peshawar	78	2026-02-15	2026-02-12
Cyclosporine Or Methotrexate for Pediatric Alopecia Areata: Routine Clinical Care Effectiveness Study Methotrexate, Cyclosporin (CSA) - Alopecia Areata(AA), Alopecia Areata (AA)	Phase 4	Recruiting	Erasmus Medical Center	50	2025-11-01	2026-02-02
Safety and Pharmacokinetic Study of ATI-50002 in Subjects With Alopecia Universalis (AU) and Alopecia Totalis (AT) Vehicle, ATI-50002 - Alopecia Universalis (AU), Alopecia Totalis (AT)	Phase 2	Completed	Aclaris Therapeutics, Inc.	11	2017-12-14	2020-07-02
Tofacitnib for the Treatment of Alopecia Areata and Variants Tofacitinib Administration - Alopecia Areata (AA), Alopecia Totalis (AT)	Phase 2	Completed	Yale University	30	2014-07-01	2017-04-04

Narrower conditions

Alopecia universalis (4)  ·  Alopecia Areata (3)

Broader conditions

Alopecia (3)  ·  Hair Diseases (3)  ·  Hypotrichosis (3)  ·  Skin Diseases (3)  ·  Skin and Connective Tissue Diseases (3)

Interventions

Methotrexate (2)  ·  Cyclosporine (1)  ·  tofacitinib (1)

Sponsors

Aclaris Therapeutics, Inc. (1)  ·  Erasmus Medical Center (1)  ·  Hayat Abad Medical Complex, Peshawar (1)  ·  Yale University (1)

Countries

United States (2)  ·  Netherlands (1)

Top investigators

Brett King, MD (1)

Results publications

PMID 22512484, PMID 22524397, PMID 24202232, PMID 26183987, PMID 27699252, PMID 28300084, PMID 29273100, PMID 29273101, PMID 29466675, PMID 29723356, PMID 29791718, PMID 30073292, PMID 33376289, PMID 7791384, PMID 8557859