Incidental Gallbladder Carcinoma :Incidence and Clinical Significance in Specimens From Routine Cholecystectomies in Sohag Locality

NCT07885800 — Recruiting, 100 participants, Sohag University

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RegistryNCT07885800
StatusRecruiting
Study typeObservational
Enrollment100 (Estimated)
SponsorSohag University (Other)
ConditionsGall Bladder Carcinoma
Interventionshistopathology of gall bladder (Other)
Datesstart 2026-09-20, primary completion 2027-05-21 (estimated), completion 2027-05-22 (estimated), first posted 2026-10-21, last updated 2026-10-21
Locations1 site in Egypt

Related Papers Related Patents Related Grants Related Experts
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-Summary

Incidental gallbladder carcinoma :Incidence and clinical significance in specimens from routine cholecystectomies in sohag locality

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+Detailed description

Gallstone disease represents one of the commonest benign biliary disorders encountered in general surgical practice, ranging from asymptomatic cholelithiasis to biliary colic, acute cholecystitis, chronic cholecystitis, pancreatitis, cholangitis, and obstructive jaundice. Laparoscopic cholecystectomy is widely accepted as the standard definitive treatment for symptomatic gallstone disease and constitutes one of the most frequently performed abdominal operations worldwide This study aims to determine the incidence of incidental gallbladder carcinoma among routine cholecystectomy specimens in Sohag and to evaluate its clinicopathological characteristics, associated risk factors, histopathological staging, and clinical significance regarding postoperative management, referral, and need for further surgical intervention.

+Arms and interventions

ArmTypeInterventionsDescription
all patient performed cholecystectomyOther: histopathology of gall bladder
  • histopathology of gall bladder (Other): histopathology of gall bladder after cholycystectomy

+Outcome measures

Primary outcomes

  • incidence of gallbladder carcinoma [6 months]: incidence of gallbladder carcinoma in histopathology

+Eligibility

Sex: All, ages: 14 Years to 70 Years, accepts healthy volunteers

Inclusion Criteria:

1. Patients undergoing cholecystectomy either lap or open or lap converted into open.
2. Patients whose gallbladder specimens are available for complete histopathological examination.
3. Patients who provide written informed consent to participate in the study.
4. Patients of both sexes and all eligible adult age groups.

Exclusion Criteria:

1. Patients with preoperatively confirmed gallbladder carcinoma.
2. Patients undergoing cholecystectomy as part of planned oncological surgery for another malignancy.
3. Patients with missing, damaged, or inadequately preserved gallbladder specimens.
4. Patients with incomplete clinical or histopathological data.
5. Patients refusing participation or postoperative follow-up.

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+Locations (1)

FacilityCityCountryStatus
Sohag UniversitySohagEgyptRecruiting