The Effects of Intermittent Positive Pressure Breathing and Incentive Spirometry on Postoperative Pulmonary Complications and Lung Volume in Patients Undergoing Thoracic Surgery: A Randomized Controlled Trial
| Registry | NCT07867548 |
|---|---|
| Status | Not yet recruiting |
| Phase | Not applicable |
| Study type | Interventional; randomized, parallel, masking: none, prevention |
| Enrollment | 30 (Estimated) |
| Sponsor | Fu Jen Catholic University Hospital (Other) |
| Conditions | Postoperative Pulmonary Complications, Thoracic Surgery |
| Interventions | Intermittent Positive Pressure Breathing, Incentive Spirometry (Other) |
| Dates | start 2026-10-12 (estimated), primary completion 2027-07-31 (estimated), completion 2027-07-31 (estimated), first posted 2026-10-09, last updated 2026-10-09 |
Related Papers Related Patents Related Grants Related Experts
All trials for Postoperative Pulmonary Complications All trials for Thoracic Surgery All trials of Intermittent Positive Pressure Breathing All trials of Incentive Spirometry
This randomized controlled pilot study will compare intermittent positive pressure breathing (IPPB) with incentive spirometry (IS) in adult patients undergoing thoracic surgery. The study aims to evaluate the effects of these two postoperative pulmonary rehabilitation interventions on lung volume recovery, respiratory muscle strength, oxygenation, pulmonary complications, and overall postoperative recovery. Participants will be randomly assigned to either the IPPB group or the IS group. Assessments will be performed before surgery and after the intervention period.
This is a single-center, randomized controlled pilot study conducted at Fu Jen Catholic University Hospital. A total of 30 adult patients undergoing thoracic surgery will be enrolled and randomly assigned to one of two intervention groups: intermittent positive pressure breathing (IPPB) or incentive spirometry (IS).
Before surgery, participants will undergo baseline assessments including blood sampling, lung volume measurement, chest X-ray, respiratory muscle strength assessment, and pulmonary function evaluation. After surgery, participants will receive the assigned pulmonary rehabilitation intervention from postoperative day 0 through postoperative day 3.
Participants assigned to the IS group will perform supervised slow and deep inspirations using an incentive spirometer 3 to 4 times per day, with three sets of 10 breaths per session. Participants will also be encouraged to practice independently while awake. Participants assigned to the IPPB group will receive intermittent positive pressure breathing as the postoperative lung expansion intervention according to the study protocol.
Follow-up assessments will be performed after the intervention period. Outcomes will include changes in lung volume; maximal inspiratory and expiratory pressures; physiologic parameters including heart rate, respiratory rate, and blood pressure; chest X-ray findings; pulmonary function; arterial blood gas measurements; peripheral oxygen saturation; dyspnea; pain; and postoperative pulmonary complications. Blood samples will also be collected to evaluate C-reactive protein as an indicator of postoperative inflammatory response.
The study is designed to evaluate the feasibility of the study procedures and to obtain preliminary estimates of treatment effects that may be used to inform the sample size and design of a future definitive randomized controlled trial.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Intermittent Positive Pressure Breathing Group | Experimental | Other: Intermittent Positive Pressure Breathing | Participants assigned to this group will receive intermittent positive pressure breathing (IPPB) as the postoperative lung expansion intervention from postoperative day 0 through postoperative day 3. |
| Incentive Spirometry Group | Active comparator | Other: Incentive Spirometry | Participants assigned to this group will perform postoperative lung expansion training using incentive spirometry from postoperative day 0 through postoperative day 3. |
Sex: All, ages: 18 Years to any, accepts healthy volunteers
Inclusion Criteria: * Willing and able to provide written informed consent. Adults aged 18 years or older. Undergoing thoracic surgery. Considered eligible by a specialist physician to participate in pulmonary rehabilitation training. Exclusion Criteria: * Unable to cooperate with the study procedures. Untreated pneumothorax. Severe hemodynamic instability. Active hemoptysis or gastrointestinal bleeding. Intracranial pressure greater than 15 mmHg. Recent facial, oropharyngeal, or cranial surgery or injury. Tracheoesophageal fistula. Recent esophageal surgery. Nausea or vomiting. Pulmonary bullae identified on imaging.