Ultrasound-guided Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Children Undergoing Elective Open Lower Abdominal Surgeries: a Randomized Comparative Clinical Trial
| Registry | NCT07853586 |
|---|---|
| Status | Recruiting |
| Phase | Not applicable |
| Study type | Interventional; randomized, parallel, masking: quadruple, supportive care |
| Enrollment | 60 (Estimated) |
| Sponsor | Menoufia University (Other) |
| Conditions | Bilateral Inguinal Hernia Repair, Open Upper Abdominal Surgeries |
| Interventions | ultrasound guided anterior oudratus lumborum block, Ultrasound guided erector spinae plane block (Procedure) |
| Dates | start 2026-10-01 (estimated), primary completion 2027-07-01 (estimated), completion 2027-07-01 (estimated), first posted 2026-10-02, last updated 2026-10-08 |
| Locations | 1 site in Egypt |
Related Papers Related Patents Related Grants Related Experts
All trials for Bilateral Inguinal Hernia Repair All trials for Open Upper Abdominal Surgeries All trials of ultrasound guided anterior oudratus lumborum block All trials of Ultrasound guided erector spinae plane block
To compare the postoperative analgesic efficacy of ultrasound-guided Quadratus Lumborum Block (anterior approach) versus Erector Spinae Plane Block (T10-T12 level), both performed bilaterally with 0.25% bupivacaine (0.5 mL/kg per side), in the first 24 hours postoperatively in children undergoing elective open lower abdominal surgery under general anesthesia.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Ultrasound guided anterior quadratus lumborum block | Active comparator | Procedure: ultrasound guided anterior oudratus lumborum block | |
| ultrasound guided erector spinae block | Active comparator | Procedure: Ultrasound guided erector spinae plane block |
Sex: All, ages: 2 Years to 7 Years
Inclusion Criteria: * Age: 2 to 7 years. * ASA Physical Status Classification I or II . * Scheduled for elective minor open lower abdominal surgery (bilateral inguinal hernia repair, orchiopexy, circumcision, bilateral hydrocele repair), pyeloplasty and ureteric reimplantation. * Weight between 10 and 25 kg. Exclusion Criteria * Known allergy or hypersensitivity to local anesthetics (amide class). * Contraindications to regional anesthesia: coagulopathy (INR > 1.5, platelets < 80,000/mm³), local infection at the injection site, or raised intracranial pressure. * Pre-existing neurological, neuromuscular, or spinal disorders. * Significant hepatic dysfunction (Child-Pugh Class B or C) or severe renal impairment (eGFR < 30 mL/min/1.73 m²). * Previous abdominal or retroperitoneal surgery which likely to distort fascial planes at the injection site. * Emergency or redo surgical procedures. * Inability to assess postoperative pain due to pre-existing developmental or cognitive impairment preventing validated pain scale use. * Intraoperative conversion from open to laparoscopic approach (post-randomization exclusion criterion).
| Facility | City | Country | Status |
|---|---|---|---|
| Menoufia University | Alexandria | Egypt | Recruiting |