Central Line-Associated Bloodstream Infection QI Project

NCT07746674 — Not yet recruiting, 30 participants, NYU Langone Health

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Central Line-Associated Bloodstream Infection (CLABSI) Quality Improvement Project

Registry	NCT07746674, acronym CLABSI
Status	Not yet recruiting
Study type	Observational
Enrollment	30 (Estimated)
Sponsor	NYU Langone Health (Other)
Conditions	Central Line-associated Bloodstream Infection (CLABSI)
Dates	start 2026-09-01 (estimated), primary completion 2026-09-01 (estimated), completion 2027-03-01 (estimated), first posted 2026-08-05, last updated 2026-08-05
Locations	1 site in United States

-Summary

This study evaluates a daily electronic health record (EHR) alert designed to reduce unnecessary central venous catheter (CVC) use among hospitalized adults. The alert identifies patients with an active CVC and no documented indication, prompting the first-contact provider to document line necessity. The study compares alert and a secure chat intervention to usual care, with the goal of reducing unnecessary line days and related CLABSI risk.

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+Arms and interventions

Arm	Type	Interventions	Description
Usual Care			Adult inpatients meeting eligibility criteria.
Secure Chat + Alert Cohort			Adult inpatients meeting eligibility criteria whose provider receives a daily EHR OPA alert and additional secure chat communication.

+Outcome measures

Primary outcomes

Total number of central line days without a documented indication [Up to Month 3]

Secondary outcomes

Number of femoral central lines in place for more than 2 days [Up to Month 3]
Number of non-tunneled hemodialysis catheters without an active hemodialysis or continuous renal replacement therapy order [Up to Month 3]

+Eligibility

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Not hospice patient class
* Active central line for at least 24 hours

Exclusion Criteria:

* No active central line
* Central line present for less than 24 hours

+Locations (1)

Facility	City	Country	Status
NYU Langone Health	New York, New York	United States

+Investigators

Holly Krelle, Principal investigator, NYU Langone Health

My Notes

Public

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