| Registry | NCT07731152 |
|---|---|
| Status | Not yet recruiting |
| Phase | Not applicable |
| Study type | Interventional; non randomized, parallel, masking: none, treatment |
| Enrollment | 40 (Estimated) |
| Sponsor | Sohag University (Other) |
| Conditions | Deviated Nasal Septum, Nasal Obstruction Septal Deviation Compensatory Inferior Turbinate Hypertrophy |
| Interventions | septoplasty, septoplasty with inferior turbinate reduction. (Procedure) |
| Dates | start 2026-09-01 (estimated), primary completion 2027-09-01 (estimated), completion 2027-09-01 (estimated), first posted 2026-07-28, last updated 2026-07-28 |
Related Papers Related Patents Related Grants Related Experts
All trials for Deviated Nasal Septum All trials for Nasal Obstruction Septal Deviation Compensatory Inferior Turbinate Hypertrophy All trials of septoplasty All trials of septoplasty with inferior turbinate reduction.
This prospective comparative study aims to evaluate the outcomes of septoplasty with or without inferior turbinate reduction in patients with symptomatic deviated nasal septum. Subjective and objective outcomes will be assessed using the NOSE score, Peak Nasal Inspiratory Flow (PNIF), and nasal endoscopic examination before and after surgery.
This prospective comparative study will be conducted at the Department of Otolaryngology, Sohag University Hospital. The study aims to compare the outcomes of septoplasty alone versus septoplasty combined with inferior turbinate reduction in adult patients with symptomatic deviated nasal septum and persistent nasal obstruction. Forty patients will be enrolled and allocated into two groups. Clinical outcomes will be evaluated preoperatively and at 1 month and 3 months postoperatively using the Nasal Obstruction Symptom Evaluation (NOSE) score, Peak Nasal Inspiratory Flow (PNIF), and diagnostic nasal endoscopy. The primary outcome is improvement in nasal obstruction symptoms, while secondary outcomes include changes in NOSE score, PNIF measurements, and endoscopic findings.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| septoplasty alone | Active comparator | Procedure: septoplasty | Patients will undergo septoplasty alone for correction of symptomatic deviated nasal septum. Postoperative outcomes will be assessed using NOSE score, Peak Nasal Inspiratory Flow (PNIF), and endoscopic examination. |
| septoplasty with inferior turbinate reduction | Active comparator | Procedure: septoplasty with inferior turbinate reduction. | Patients will undergo septoplasty combined with inferior turbinate reduction for correction of symptomatic deviated nasal septum with associated inferior turbinate hypertrophy. Postoperative outcomes will be assessed using NOSE score, Peak Nasal Inspiratory Flow (PNIF), and endoscopic examination. |
Sex: All, ages: 18 Years to 50 Years
Inclusion Criteria: * Patients with symptomatic deviated nasal septum causing persistent nasal obstruction, aged 18-50 years, who failed medical treatment for at least 3 months, will be included in the study. Exclusion Criteria: * Patients with previous nasal surgery, nasal polyposis, chronic rhinosinusitis, alar collapse, uncontrolled allergic rhinitis, nasal tumors, or external nasal deformity requiring rhinoplasty will be excluded from the study.