HFCWO in Children With Non-CF Bronchiectasis

NCT07722364 — Not applicable, Not yet recruiting, 60 participants, Sphinx university

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Effect of High Frequency Chest Wall Oscillation on Pulmonary Functions in Children With Non-Cystic Fibrosis Bronchiectasis

RegistryNCT07722364
StatusNot yet recruiting
PhaseNot applicable
Study typeInterventional; randomized, parallel, masking: triple, treatment
Enrollment60 (Estimated)
SponsorSphinx university (Other)
ConditionsNon Cystic Fibrosis Bronchiectasis
InterventionsHigh Frequency Chest Wall Oscillation, conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life. (Device, other)
Datesstart 2026-07-01 (estimated), primary completion 2026-12-01 (estimated), completion 2027-01-01 (estimated), first posted 2026-07-23, last updated 2026-07-28
Locations1 site in Egypt

Related Papers Related Patents Related Grants Related Experts
All trials for Non Cystic Fibrosis Bronchiectasis All trials of High Frequency Chest Wall Oscillation All trials of conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life.

-Summary

the study will concentrate on the effect of High Frequency Chest Wall Oscillation compared to conventional pulmonary physiotherapy on children with non cystic fibrosis bronchiectasis

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+Detailed description

The purpose of this study is to evaluate the effect of using HFCWO intervention on pulmonary functions in children with bronchiectasis.

it hypothesized that Using HFCWO has no effect on pulmonary functions and hospital stay in children with bronchiectasis.

Children subjected to the inclusion criteria will be assigned randomly into two groups, control group and study group.

Does high frequency chest wall oscillation (HFCWO) have an effect in pulmonary functions in children with bronchiectasis? RCT study Control group Patients in this group will be 30 children who will be treated by conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life.

Study group This group will include 30 children who will use HFCWO for 20 minutes, in addition to 10 minutes of the same conventional program of physiotherapy given to the control group.

The frequency of treatment will be 5 sessions/week for three successive months for both groups for long term effect and daily for immediate effect.

outcome measure: FEV1, FVC, FEV1/FVC quality of life for bronchiectasis, 6-minute walk test

+Arms and interventions

ArmTypeInterventionsDescription
children who will use HFCWO for 20 minutes, in addition to 10 minutes of the same conventional progrExperimentalDevice: High Frequency Chest Wall OscillationThis group will include 30 children who will use HFCWO for 20 minutes, in addition to 10 minutes of the same conventional program of physiotherapy given to the control group. The frequency of treatment will be 5 sessions/week for three successive months for both groups for long term effect and daily for immediate effect.
children who will be treated by conventional physiotherapy programActive comparatorOther: conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life.Patients in this group will be 30 children who will be treated by conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life.
  • High Frequency Chest Wall Oscillation (Device): High-frequency chest wall oscillation that applies external chest wall oscillations via an inflatable vest worn around the thoracic cage, increasing the air-liquid shear forces during expiration is believed to result in secretion mobilization. The product name that will be used is Air Way Clearness system; his model is PV-900/ PV-300/PV-100, made in China.
  • conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life. (Other): conventional physiotherapy program directed towards improvement of pulmonary functions and quality of life. Conventional physiotherapy that will be applied to the control group for 30 minutes will include: * Postural drainage according to accumulation of secretions for 10 minutes accompanied by percussion or vibration * Active cycle breathing technique (ACBT) for 10 minutes * Respiratory exercises for 10 minutes

+Outcome measures

Primary outcomes

  • Forced Expiratory Volume in 1 second (FEV1) [Baseline and after 8 weeks of treatment]: Change in FEV1 measured by spirometry according to ATS/ERS guidelines
  • Forced Vital Capacity (FVC) [Baseline and after 6 months of treatment]: Change in FVC measured by spirometry according to ATS/ERS guidelines
  • FEV1/FVC Ratio [Baseline and after 6 months of treatment]: Change in FEV1/FVC ratio measured by spirometry according to ATS/ERS guidelines

Secondary outcomes

  • Six-Minute Walk Distance (6MWD) [Baseline and after 6 months of treatment]: hange in functional exercise capacity assessed by the Six-Minute Walk Test (6MWT). The total distance walked in six minutes is recorded according to the American Thoracic Society (ATS) guidelines.

+Eligibility

Sex: All, ages: 6 Years to 12 Years

Inclusion Criteria:

* • Children with no cystic fibrosis bronchiectasis

  * Both sexes
  * Their ages ranges from 6-12 years
  * After 48 hours of attack, if hemoptysis or fever not found

Exclusion Criteria:

* • Osteoporosis (Calcium deficiency)

  * Bleeding tendency
  * Recent surgery of brain, eye, thoracic, or neck surgery
  * Pneumothorax
  * Cystic fibrosis bronchiectasis
  * Pulmonary embolism
  * Rib fracture

+Locations (1)

FacilityCityCountryStatus
pediatric hospital, Assiut universityAsyutEgypt