Effects of Pulmonary Rehabilitation Versus Standard Care in Patients With Pericarditis

NCT07716696 — Not applicable, Active not recruiting, 60 participants, University of Lahore

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Comparative Effects of Pulmonary Rehabilitation Versus Standard Care on Pain, Dyspnea, Cough Severity, Fatigue, and Anxiety in Patients With Pericarditis: A Randomized Controlled Trial

Registry	NCT07716696
Status	Active not recruiting
Phase	Not applicable
Study type	Interventional; randomized, parallel, masking: single, treatment
Enrollment	60 (Estimated)
Sponsor	University of Lahore (Other)
Conditions	Pericarditis
Interventions	Pulmonary Rehabilitation, Standard Care (Other)
Dates	start 2025-12-11, primary completion 2026-09-15 (estimated), completion 2026-10-16 (estimated), first posted 2026-07-21, last updated 2026-07-21
Locations	1 site in Pakistan

-Summary

Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life. Pulmonary rehabilitation is a structured intervention designed to improve respiratory function and overall physical performance. This study aims to compare the effectiveness of pulmonary rehabilitation versus standard care in improving clinical symptoms and functional outcomes in patients with pericarditis.

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+Detailed description

This randomized controlled trial evaluates the comparative effectiveness of pulmonary rehabilitation and standard care in patients diagnosed with pericarditis. Participants are allocated into two groups: an intervention group receiving pulmonary rehabilitation and a control group receiving standard medical care.

Pulmonary rehabilitation includes breathing exercises, aerobic training, and patient education aimed at improving respiratory efficiency and reducing symptom burden. Such programs are widely used to improve functional capacity and quality of life in clinical populations \[1\].

Outcome measures include pain intensity, dyspnea, cough severity, fatigue, and anxiety, assessed using validated tools such as the Visual Analog Scale (VAS) and McMaster Cough Severity Questionnaire.

Assessments will be conducted at baseline and after completion of the intervention period.

+Arms and interventions

Arm	Type	Interventions	Description
Pulmonary Rehabilitation Group	Experimental	Other: Pulmonary Rehabilitation	Participants receive a structured pulmonary rehabilitation program including breathing exercises, aerobic training, and education sessions.
Standard Care Group	Active comparator	Other: Standard Care	Routine clinical management as prescribed by the treating physician without additional rehabilitation protocol.

Pulmonary Rehabilitation (Other): A structured program including breathing exercises, aerobic conditioning, and patient education administered over multiple weeks.
Standard Care (Other): Routine clinical management as prescribed by the treating physician without additional rehabilitation protocol.

+Outcome measures

Primary outcomes

Dyspnea Severity [Baseline and 8 weeks]: Measured using Visual Analog Scale (VAS)

Secondary outcomes

Pain Intensity [Baseline and 8 weeks]: Measured using VAS
Cough Severity [Baseline and 8 weeks]: Measured using McMaster Cough Severity Questionnaire
Fatigue [Time Frame: Baseline and 8 weeks]: Measured using VAS or standardized fatigue scale
Anxiety [Time Frame: Baseline and 8 weeks]: Measured using a validated anxiety scale

+Eligibility

Sex: All, ages: 18 Years to 65 Years

Inclusion Criteria:

Diagnosed with pericarditis Age between 18-65 years Both male and female participants Medically stable Able to participate in rehabilitation Willing to provide informed consent

Exclusion Criteria:

Severe cardiovascular or respiratory instability Other major pulmonary diseases Recent surgery or trauma Neurological disorders affecting participation Unwillingness to participate

+Locations (1)

Facility	City	Country	Status
ULTH	Lahore, Punjab Province	Pakistan