Diurnal Strength Variation

NCT07711340 — Not applicable, Suspended, 20 participants, Stanford University

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Exercise Timing and Lower Limb Biomechanics

Registry	NCT07711340
Status	Suspended - no personnel to current run this study
Phase	Not applicable
Study type	Interventional; randomized, crossover, masking: single, basic science
Enrollment	20 (Estimated)
Sponsor	Stanford University (Other)
Conditions	Healthy Adult, Exercise
Interventions	Time-driven dosing (Behavioral)
Dates	start 2026-08-01, primary completion 2027-09-30 (estimated), completion 2027-12-31 (estimated), first posted 2026-07-17, last updated 2026-09-28
Locations	1 site in United States

-Summary

Healthy individuals will be tested at different times of day to determine whether exercise at a non-expected time results in poorer performance.

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+Arms and interventions

Arm	Type	Interventions	Description
Regular Exercise	No intervention		Exercise at the usual time
Early Exercise	Experimental	Behavioral: Time-driven dosing	Exercise three hours earlier than usual
Exercise Late	Experimental	Behavioral: Time-driven dosing	Exercise three hours later than usual

Time-driven dosing (Behavioral): Three hours earlier or later than usual exercise

+Outcome measures

Primary outcomes

Isometric quadriceps strength [15 minutes]: isometric quadriceps strength as determined during dynamometer testing

Secondary outcomes

Isometric hamstring strength [15 minutes]: Hamstring strength as determined during dynamometer testing
Isokinetic hamstring/quad strength [15 minutes]: Hamstring/quad strength as determined during dynamometer testing

+Eligibility

Sex: All, ages: 18 Years to 25 Years, accepts healthy volunteers

Inclusion Criteria:

* Healthy
* 18-25 years old
* Lower body exercise three or more times per week, all at the same time of day (within 2 hour window)
* Regular meal times (±1 hour window)
* Regular sleep times (±1 hour window)

Exclusion Criteria:

* Active or uncontrolled mental or physical health issues
* Current musculoskeletal injury

+Locations (1)

Facility	City	Country	Status
Stanford University	Stanford, California	United States