Effects of Fried Foods Prepared in Palm Oil Blended With Canola Oil Containing Surfactants and Green Tea Extract on Postprandial Triglyceride Levels: A Double-blinded Randomized Controlled Clinical Trial
| Registry | NCT07674602 |
|---|---|
| Status | Completed |
| Phase | Not applicable |
| Study type | Interventional; randomized, parallel, masking: triple, prevention |
| Enrollment | 22 (Actual) |
| Sponsor | Chulalongkorn University (Other) |
| Conditions | Healthy Adult Participants |
| Interventions | Fried Foods Prepared in Palm Oil Blended With Canola Oil Containing Surfactants and Green Tea Extract, Fried Foods Prepared in Palm Oil (Other) |
| Dates | start 2025-11-01, primary completion 2026-03-31, completion 2026-04-15, first posted 2026-06-29, last updated 2026-06-29 |
| Locations | 1 site in Thailand |
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The objectives of the study were to investigate effects of foods prepared in palm oil blended with canola oil containing surfactants and green tea extract on postprandial triglyceride levels in healthy volunteers. There were 22 subjects in the study. They were divided into 2 groups: 1.comsumed foods fried in palm oil blended with canola oil containing surfactants and green tea extract and 2.comsumed foods fried in palm oil. Postprandial triglyceride, lipid profiles, and liver and kidney functions were evaluated before and after taking 5 hours.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Fried Foods Prepared in Palm Oil Blended With Canola Oil Containing Surfactants and Green Tea Extrac | Experimental | Other: Fried Foods Prepared in Palm Oil Blended With Canola Oil Containing Surfactants and Green Tea Extract | Take fried foods prepared in palm oil blended with canola oil containing surfactants and green tea extract 7 pieces. |
| Control group | Active comparator | Other: Fried Foods Prepared in Palm Oil | Take fried foods prepared in palm oil 7 pieces |
Sex: All, ages: 18 Years to 60 Years, accepts healthy volunteers
Inclusion Criteria: * Male or female participants aged 18-60 years. * Participants with fasting triglyceride levels <150 mg/dL (after fasting for at least 8-12 hours before blood collection). * Participants without a history of cardiovascular disease, diabetes mellitus, thyroid disease, cancer, liver disease, or kidney disease. * Participants who are able to read and write. * Participants who voluntarily agree to participate after receiving information regarding the study objectives, procedures, potential risks, and expected benefits; are able to comply with the study protocol; and provide written informed consent. Exclusion Criteria: * Participants with a history of allergy or adverse reactions, such as skin, respiratory, or gastrointestinal symptoms, after consuming foods containing canola oil, polyglycerol esters of fatty acids (PGEs), green tea extract, palm oil, or banana. * Participants who have consumed medications, dietary supplements, herbal products, or foods that may affect metabolism, such as weight-loss products or L-carnitine, within 2 weeks prior to enrollment. * Participants who regularly use medications that may affect lipid metabolism or blood lipid levels, such as corticosteroids or lipid-lowering agents. * Participants with serious underlying diseases or poorly controlled medical conditions, such as cancer, cardiovascular disease, or immunodeficiency disorders. * Participants with impaired liver or kidney function, defined as AST/ALT levels >3 times the upper limit of normal or kidney disease with an estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m². * Female participants who are pregnant or breastfeeding. * Participants who regularly smoke. * Participants who regularly consume alcohol. * Participants who are currently participating in another research study.
| Facility | City | Country | Status |
|---|---|---|---|
| Chulalongkorn University | Bangkok | Thailand |