Association Between Oral Hypofunction, Sarcopenia and Social Frailty in Community-dwelling Older Adults

NCT07658625 — Completed, 200 participants, Chang Gung University of Science and Technology

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Association Between Oral Hypofunction, Sarcopenia, and Social Frailty in Community-Dwelling Older Adults

Registry	NCT07658625, acronym OSSF
Status	Completed
Study type	Observational
Enrollment	200 (Actual)
Sponsor	Chang Gung University of Science and Technology (Other)
Conditions	Non Sarcopenic Subjects, Possible Sarcopenia, Sarcopenia(With Low ASM by BIM)
Interventions	Non interventional study (Other)
Dates	start 2025-11-14, primary completion 2026-06-04, completion 2026-06-04, first posted 2026-06-22, last updated 2026-06-22
Locations	1 site in Taiwan

-Summary

Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community. due to the interaction between physiological and social factors, this study aims to conduct a correlation study on muscle mass, oral function and social frailty in the elderly living in the community.

This study，the Makizako social frailty screening index questionnaire and the Tilburg Frailty Indicator will be used to assess the social frailty status of the study participants. Correlation analysis with sarcopenia and oral dysfunction was also conducted to better understand the interaction between nutrition, physiology, and social connection in the elderly, which will be helpful for formulating relevant policies and promoting healthy aging in the future in extremely elderly countries.

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+Arms and interventions

Arm	Type	Interventions	Description
Group A		Other: Non interventional study	Possible sarcopenia
Group B		Other: Non interventional study	Non-possible sarcopenia

Non interventional study (Other): NON

+Outcome measures

Primary outcomes

Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established. [Baseline]: * The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women * 6-meter walking speed less than 1.0 second/meter * 5-time chair stand test greater than or equal to 12 seconds * Short physical performance battery, SPPB greater than or equal to 9 points The above will be combined to determine whether sarcopenia is possible.

+Eligibility

Sex: All, ages: 65 Years to any, accepts healthy volunteers

Group A-Inclusion Criteria:

* 65 years old or above
* general public or institutionalized for 3 months or more
* those who accept the experimental design and are willing to sign the consent form
* dietary sources are oral intake
* those who are diagnosed as having possible sarcopenia by researchers

Group B-Inclusion Criteria:

* 65 years old or above
* general public or institutionalized for 3 months or more
* those who accept the experimental design and are willing to sign the consent form
* dietary sources are oral intake
* those who were determined by researchers to be non-probable sarcopenia

Group A、B-Exclusion Criteria:

* comorbidities, critical illness, pre- and post-major surgery, cancer, renal failure, liver failure, kidney disease, liver disease, malignant tumors within the past five years, inflammatory conditions (c-reactive protein >10mg/dL)
* severely malnourished people
* long-term force-feeding

+Locations (1)

Facility	City	Country	Status
Chang Gung University of Science and Technology	Taoyuan	Taiwan