A Study Of Starting Strength Barbell Training

• Progressive Barbell Strength Training (Other): Subjects will participate in a 12-week barbell training program, 3 days per week for approximately 60 minutes each session. Training sessions will be conducted by Starting Strength certified coaches at Starting Strength Scottsdale gym. Core barbell movements including but not limited to: squat, deadlift, bench press, overhead press, and power clean.

Primary outcomes

• Change in systolic blood pressure [Baseline, 16 weeks]: Blood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)
• Change in diastolic blood pressure [Baseline, 16 weeks]: Blood pressure will be measured using automated oscillometric device, and reported in millimeters of mercury (mmHg)

Secondary outcomes

• Change in total cholesterol [Baseline, 16 weeks]: Total cholesterol is the sum of a person's HDL cholesterol, LDL cholesterol, and 20% of their triglyceride levels. Healthy total cholesterol is less than 200 mg/dL of blood
• Change in low-density lipoprotein cholesterol (LDL-C) [Baseline, 16 weeks]: Low-density lipoprotein cholesterol (HDL-C) is measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 100 mg/DL and below are considered healthier.
• Change in high-density lipoprotein cholesterol (HDL-C) [Baseline, 16 weeks]: High-density lipoprotein cholesterol (HDL-C) is measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 60 mg/DL and above are considered healthier.
• Change in triglycerides [Baseline, 16 weeks]: Triglycerides are measured via blood sample and reported in milligrams per deciliter (mg/DL). Results 150 mg/DL and below are considered normal levels.
• Change in fasting glucose [Baseline, 16 weeks]: Blood sample taken after an overnight fast. Reported in millimoles per liter (mmol/l)

Sex: All, ages: 15 Years to 100 Years, accepts healthy volunteers

Inclusion Criteria:

* Adults aged 18-100 years
* Sedentary or minimally active (less than 150 minutes of moderate-intensity physical activity per week)
* No participation in structured resistance training programs within the past 6 months.
* Able to safely participate in resistance training as determined by medical screening
* Willing to commit to 3 training sessions per week for 12 weeks
* Able to provide informed consent
* Willing to obtain pre- and post-intervention laboratory tests from the same laboratory company.

Exclusion Criteria:

* Current participation in structured resistance training programs
* Cardiovascular disease requiring activity restriction
* Uncontrolled hypertension (systolic BP >180 mm Hg or diastolic BP >110 mm Hg)
* Musculoskeletal conditions precluding safe barbell training
* Changes in lipid-lowering or antihypertensive medications within 3 months prior to enrollment
* Known cardiovascular, metabolic, or renal disease that would preclude safe participation in resistance training

• Joshua Lee, PA-C,MPAS, Principal investigator, Mayo Clinic