Laser-Based Map Tests in Motoric Cognitive Risk Syndrome

NCT07572942 — Recruiting, 35 participants, Balikesir University

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Validity and Reliability of Neuroscience-Based Visual Laser Feedback Map Tests in Individuals With Motoric Cognitive Risk Syndrome

Registry	NCT07572942
Status	Recruiting
Study type	Observational
Enrollment	35 (Estimated)
Sponsor	Balikesir University (Other)
Conditions	Motoric Cognitive Risk Syndrome, Cognitive-Motor Interaction, Sensorimotor Performance
Dates	start 2026-04-15, primary completion 2026-04-28, completion 2026-07-15 (estimated), first posted 2026-05-07, last updated 2026-05-07
Locations	1 site in Turkey (Türkiye)

-Summary

This study aims to evaluate the validity and reliability of neuroscience-based visual laser feedback map tests in individuals with Motoric Cognitive Risk Syndrome (MCRS). The developed assessment protocol integrates visuospatial processing, reaction time, and upper extremity motor control within a single task. Construct validity will be examined through correlations with reaction time and proprioception measurements, and test-retest reliability will be assessed to determine measurement consistency.

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+Arms and interventions

Arm	Type	Interventions	Description
Motoric Cognitive Risk Syndrome Group			Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome (MCRS) will be included. Participants will undergo neuroscience-based visual-laser feedback map tests along with reaction time and proprioception assessments under standardized conditions. No therapeutic intervention will be applied.

+Outcome measures

Primary outcomes

Visual-laser feedback map test performance [Baseline]: Performance parameters including completion time (seconds), reaction time (milliseconds), movement accuracy, and total performance score obtained from the figure-of-eight tracing and directional target tracking tasks.

Secondary outcomes

Reaction time [Baseline]: Reaction time will be assessed using the Light Trainer system. The response time to visual stimuli will be recorded in milliseconds.
Shoulder proprioception [Baseline]: Shoulder joint position sense will be assessed using the joint repositioning test. Absolute error will be recorded in degrees.
Test-retest reliability [Baseline and 7-day follow-up]: Test-retest reliability of the visual-laser feedback map tests will be evaluated using the Intraclass Correlation Coefficient (ICC).
Measurement error [Baseline and 7-day follow-up]: Measurement error will be calculated using the Standard Error of Measurement (SEM) and Minimal Detectable Change (MDC).

+Eligibility

Sex: All, ages: 65 Years to any

Inclusion Criteria:

Aged ≥65 years Diagnosis of Motoric Cognitive Risk Syndrome (subjective cognitive complaint + slow gait) Living independently in the community Able to understand and perform test procedures

Exclusion Criteria:

Diagnosed dementia Severe psychiatric disorders Advanced visual impairments (e.g., macular degeneration, severe cataract) Neurological disorders affecting motor control Severe tremor or ataxia interfering with task performance

+Locations (1)

Facility	City	Country	Status
Balikesir University	Balıkesir, Bigadiç	Turkey (Türkiye)	Recruiting

+Publications

Pinzón-Ríos, I. D., & Moreno-Collazos, J. E. (2020). Neural aging, brain plasticity and exercise: Advances from a physiotherapy perspective. Archivos de Medicina (Manizales), 20(1), 188-202.
Koo TK, Li MY. A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. J Chiropr Med. 2016 Jun;15(2):155-63. doi: 10.1016/j.jcm.2016.02.012. Epub 2016 Mar 31. PMID 27330520
Shadmehr R, Krakauer JW. A computational neuroanatomy for motor control. Exp Brain Res. 2008 Mar;185(3):359-81. doi: 10.1007/s00221-008-1280-5. Epub 2008 Feb 5. PMID 18251019
Moinuddin A, Goel A, Sethi Y. The Role of Augmented Feedback on Motor Learning: A Systematic Review. Cureus. 2021 Nov 18;13(11):e19695. doi: 10.7759/cureus.19695. eCollection 2021 Nov. PMID 34976475
Clark DJ. Automaticity of walking: functional significance, mechanisms, measurement and rehabilitation strategies. Front Hum Neurosci. 2015 May 5;9:246. doi: 10.3389/fnhum.2015.00246. eCollection 2015. PMID 25999838
Seidler RD, Bernard JA, Burutolu TB, Fling BW, Gordon MT, Gwin JT, Kwak Y, Lipps DB. Motor control and aging: links to age-related brain structural, functional, and biochemical effects. Neurosci Biobehav Rev. 2010 Apr;34(5):721-33. doi: 10.1016/j.neubiorev.2009.10.005. Epub 2009 Oct 20. PMID 19850077