The Effect of Sunflower and Olive Oils on Diaper Dermatitis in Hospitalized Infants Treated With Antibiotics: A Quasi-Experimental Study
| Registry | NCT07517003, acronym DD-OIL |
|---|---|
| Status | Completed |
| Phase | Not applicable |
| Study type | Interventional; non randomized, parallel, masking: none, prevention |
| Enrollment | 150 (Actual) |
| Sponsor | Dicle University (Other) |
| Conditions | Diaper Dermatitis |
| Interventions | Sunflower Oil, Olive Oil, Routine Care (Other) |
| Dates | start 2024-01-20, primary completion 2024-07-31, completion 2024-07-31, first posted 2026-04-08, last updated 2026-08-27 |
| Locations | 1 site in Turkey (Türkiye) |
Related Papers Related Patents Related Grants Related Experts
All trials for Diaper Dermatitis All trials of Sunflower Oil All trials of Olive Oil
This quasi-experimental study aimed to evaluate the effects of sunflower oil and olive oil on the development of diaper dermatitis in hospitalized infants receiving antibiotic therapy. Infants aged 0-24 months were assigned to sunflower oil, olive oil, and control groups. Oils were applied to the diaper area after each diaper change. Infants were followed daily for 3-7 days, and diaper dermatitis severity was assessed using a four-stage clinical classification. The incidence of diaper dermatitis was compared between groups.
Diaper dermatitis is a common skin condition in infants and occurs more frequently in hospitalized infants receiving systemic antibiotics. This quasi-experimental study evaluated the preventive effects of sunflower oil and olive oil on diaper dermatitis. The study included 150 infants aged 0-24 months hospitalized and receiving antibiotic therapy. Participants were assigned to three groups: sunflower oil, olive oil, and control. In the intervention groups, oils were applied to the diaper area after each diaper change, while the control group received routine care. Infants were followed daily for 3-7 days, and diaper dermatitis severity was assessed using a four-stage clinical classification. The primary outcome was the incidence of diaper dermatitis. The study aimed to determine whether sunflower oil and olive oil reduce diaper dermatitis in hospitalized infants.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Sunflower Oil | Experimental | Other: Sunflower Oil | Participants received sunflower oil applied to the diaper area after each diaper change during hospitalization. |
| Olive Oil | Experimental | Other: Olive Oil | Participants received olive oil applied to the diaper area after each diaper change during hospitalization. |
| Control | Active comparator | Other: Routine Care | Participants received routine diaper care without topical oil application. |
Sex: All, ages: 0 Months to 24 Months
Inclusion Criteria: * Infants aged 0-24 months * Hospitalized and receiving systemic antibiotic therapy * Expected hospital stay of 3-7 days * Using disposable diapers * Written informed parental consen Exclusion Criteria: * Premature or low birth weight infants * Existing diaper dermatitis * Diarrhea or oral candidiasis * Chronic skin diseases (eczema, atopy, seborrheic dermatitis) * Receiving antifungal treatment * Neurological or urological anomalies * Use of urinary catheter or bag * Toilet-trained infants
| Facility | City | Country | Status |
|---|---|---|---|
| Midyat State Hospital | Midyat, Mardin | Turkey (Türkiye) |