The Value of [18F]FDG PET/CT Imaging in Prognostic Evaluation of Mucosal Melanoma

NCT07506447 — Completed, 68 participants, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

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Registry	NCT07506447
Status	Completed
Study type	Observational
Enrollment	68 (Actual)
Sponsor	Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (Other)
Conditions	FDG PET, Mucosal Melanoma
Interventions	Telephone follow-up (Other)
Dates	start 2021-01-01, primary completion 2025-05-08, completion 2026-03-13, first posted 2026-04-01, last updated 2026-04-01
Locations	1 site in China

-Summary

This project will target patients with histopathologically diagnosed mucosal melanoma using \[¹⁸F\]FDG PET/CT imaging for retrospective prognostic evaluation.The primary objective is to explore the value of \[¹⁸F\]FDG PET/CT imaging in the prognostic assessment of mucosal melanoma, and to determine the correlations between quantitative \[¹⁸F\]FDG PET parameters and progression-free survival (PFS) as well as overall survival (OS), so as to provide reference evidence for individualized treatment decision-making.

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+Arms and interventions

Arm	Type	Interventions	Description
Mucosal Melanoma Cohort		Other: Telephone follow-up	Retrospective cohort of mucosal melanoma patients who underwent \[18F\]FDG PET/CT for prognostic evaluation.

Telephone follow-up (Other): Telephone follow-up

+Outcome measures

Primary outcomes

Overall survival [Up to 4 years]: Overall survival (OS) is defined as the time elapsed from the date of the ¹⁸F-FDG PET/CT examination to the date of death.
Progression-free survival [Up to 4 years]: Progression-free survival (PFS) is defined as the time from the date of \[18F\]FDG PET/CT imaging to the earliest date of disease progression, recurrence, or death.

+Eligibility

Sex: All, ages: 18 Years to any

Inclusion Criteria:

1. Patients with histopathologically confirmed mucosal melanoma.

Exclusion Criteria:

1. Having another primary malignancy (other than mucosal melanoma).
2. Being lost to follow-up.
3. Being under 18 years of age.
4. Being pregnant or breastfeeding.

+Locations (1)

Facility	City	Country	Status
Wuhan Union Hospital	Wuhan, Hubei	China