Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes

NCT07374575 — Not yet recruiting, 500 participants, Cairo University

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Assessment of Knowledge, Attitudes, and Perceived Barriers Regarding the Oral Microbiome and Exosomes Among Egyptian Dental Professionals: A Cross-Sectional Questionnaire Study

Registry	NCT07374575
Status	Not yet recruiting
Study type	Observational
Enrollment	500 (Estimated)
Sponsor	Cairo University (Other)
Conditions	Oral Health
Dates	start 2027-01-20 (estimated), primary completion 2027-01-25 (estimated), completion 2027-01-30 (estimated), first posted 2026-01-29, last updated 2026-03-19

-Summary

This study employs a structured, validated questionnaire as the index test to objectively assess dental professionals' knowledge of the oral microbiome and exosomes, alongside attitudes, readiness, and perceived barriers. The primary aim is to develop and compare Microbiome Knowledge Scores (MKS) and Exosome Knowledge Scores (EKS) across dental specialties, workplace settings, and years of practice. Secondary aims include evaluating attitudes and perceived barriers, assessing the relationship between self-rated and objective knowledge, and identifying predictors of higher knowledge levels. The study tests the null hypotheses that MKS/EKS do not differ across demographic or practice characteristics and that self-rated knowledge does not correlate with objective knowledge.

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+Outcome measures

Primary outcomes

Microbiome Knowledge Score (MKS) [1 month]
Exosome Knowledge Score (EKS) [1 month]

+Eligibility

Sex: All, ages: 18 Years to any, accepts healthy volunteers

Inclusion Criteria:

* Licensed dentists practicing in Egypt (general dentists and all specialties)
* age ≥18.

Exclusion Criteria:

* Undergraduate students/interns without a license
* dentists currently practicing abroad; duplicate entries.